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  • Pancreatic intraepithelial neoplasia in heterotopic pancreas: incidentally diagnosed on endoscopic mucosal resection of a duodenal polyp

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CASE REPORT
Pancreatic intraepithelial neoplasia in heterotopic pancreas: incidentally diagnosed on endoscopic mucosal resection of a duodenal polyp
  1. Sarah Safadi1,
  2. David R Martin2,
  3. Tarun Rustagi3
  1. 1Department of Internal Medicine, University of New Mexico Hospital, Albuquerque, New Mexico, USA
  2. 2Department of Pathology, University of New Mexico Hospital, Albuquerque, New Mexico, USA
  3. 3Division of Gastroenterology and Hepatology, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA
  1. Correspondence to Dr Tarun Rustagi, tarunrustagi06{at}gmail.com

Summary

Heterotopic pancreas is the presence of pancreatic tissue outside its normal location. It can develop similar pathological conditions that develop in the normal pancreas, including adenocarcinoma and its precursor lesions. Due to the rarity of the condition, the diagnosis can be challenging, and treatment is not well established. ​We present a 47-year-old female patient referred for endoscopic resection of a 2 cm polyp in the second part of her duodenum. Complete endoscopic mucosal resection (EMR) was performed, with pathology revealing low-grade pancreatic intraepithelial neoplasia (PanIN) in heterotopic pancreatic tissue. To the best of our knowledge, this is the first case of heterotopic pancreas with low-grade PanIN in the duodenum to be incidentally diagnosed and treated with EMR.

  • endoscopy
  • pancreas and biliary tract
  • small intestine
  • EMR
  • endoscopic mucosal resection
  • duodenal adenoma

https://doi.org/10.1136/bcr-2018-224414

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    Footnotes

    • Contributors SS, DRM and TR have all contributed significantly to planning and writing this case. TR performed the endoscopic procedure, DRM provided the pathology images, and all authors drafted and revised the article. They all agreed on the final version submitted.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.