Article Text
Abstract
Portomesenteric thrombosis is an important but rarely reported complication following bariatric surgery. It has been suggested that the incidence of portal vein thrombosis is directly related to many risk factors inherent in the bariatric population as well as factors related to local and systemic effects of laparoscopic surgery. Possible aetiologies vary from systemic inherited hypercoagulable states to a direct inflammatory reaction of portosystemic vessels. Here we present a case report of a 47-year-old obese women who underwent a robotic sleeve gastrectomy with subsequent development of a main portal vein, complete right intrahepatic portal vein and splenic vein thrombosis ultimately found to have a compound mutation of the methylenetetrahydrofolate reductase C677T and A1298C alleles.
- gastrointestinal surgery
- genetics
- portal vein
- haematology (incl blood transfusion)
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Contributors This content has not been published or submitted for publication elsewhere except as a brief abstract in the proceedings of a scientific meeting or symposium. All authors have contributed significantly, and all authors are in agreement with the content of the manuscript. Conception and design, acquisition of data or analysis and interpretation of data: OJ, DL: drafting the article or revising it critically for important intellectual content: OJ, DL, VM, BB: final approval of the version published: OJ, DL, VM, BB: agreement to be accountable for the article and to ensure that all questions regarding the accuracy or integrity of the article are investigated and resolved: OJ, DL, VM, BB
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent for publication Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.