We continue to shine a light on some interesting pathology case reports that have been published over the years with the regular showcasing of an article together with a link to some questions and answers to help you in your education.
Case 4: Inflammatory bowel disease-like colitis pathology in a patient with common variable immune deficiency
- Common variable immunodeficiency (CVID) can affect any level of the gastrointestinal tract. Which pathological features may be helpful in differentiating CVID from coeliac disease?
- A phenotypic approach to categorising common variable immunodeficiency (CVID) has been proposed, based upon the type of complications the patient develops. What are these five proposed phenotypic categories?
- Gastrointestinal disease is identified in approximately 10 to 20 percent of CVID patients and may be the presenting disorder in some. Diarrhoea is the most common symptom, with malabsorption and weight loss also reported. Vitamin and electrolyte deficiencies may be seen in severe cases. What are the major gastrointestinal disorders in adult patients with CVID (in decreasing order of prevalence)?