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Mandibular tumour as the primary manifestation of an occult adenocarcinoma
  1. Harpreet Kaur1,
  2. Deepika Mishra1,
  3. Smita Manchanda2 and
  4. Ongkila Bhutia3
  1. 1Department of Oral Pathology and Microbiology, All India Institute of Medical Sciences, New Delhi, India
  2. 2Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India
  3. 3Department of Oral and Maxillofacial Surgery, All India Institute of Medical Sciences, New Delhi, India
  1. Correspondence to Dr Deepika Mishra; deepika1904{at}gmail.com

Abstract

Oral cavity is an uncommon site for occurrence of metastasis and usually indicates widespread systemic disease. Primary tumours from the lung most commonly metastasise to oral soft tissues (31.3%) and jaw bones (22%) among men. It is quite challenging to diagnose a solitary metastatic lesion and to determine the site of primary lesion, due to the rarity of these occurrences. This case report describes the jaw bone as a first sign of occult primary lung adenocarcinoma with multiple metastases in 47-year-old man. The patient was treated with the combination of carboplatin and paclitaxel, and has completed two cycles till date with a stable clinical course. Diagnosis of metastatic carcinoma of jaw is very challenging. The pathologist must have knowledge of ancillary techniques along with clinical, radiological and histological correlation to determine the origin of distant primary.

  • cancer - see oncology
  • dentistry and oral medicine
  • lung cancer (oncology)
  • pathology

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Footnotes

  • Contributors DM did conception and design of the case, gave final approval and is the guarantor of manuscript. HK, DM, SM and OB performed acquisition of data (laboratory or clinical/literature search), analysis and interpretation of data collected, and drafting of article and critical revision.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer-reviewed.