[HTML][HTML] DNA methylation and gene expression dynamics during spermatogonial stem cell differentiation in the early postnatal mouse testis
N Kubo, H Toh, K Shirane, T Shirakawa, H Kobayashi… - Bmc Genomics, 2015 - Springer
Background In the male germline, neonatal prospermatogonia give rise to spermatogonia,
which include stem cell population (undifferentiated spermatogonia) that supports …
which include stem cell population (undifferentiated spermatogonia) that supports …
Coming soon to a city near you! Learning to live 'beyond growth'in Japan's shrinking regions
P Matanle, Y Sato - Social Science Japan Journal, 2010 - academic.oup.com
This article analyses rural depopulation in Japan and its implications by means of a case
study of Niigata Prefecture and Sado Island. In the first part of the article, we present …
study of Niigata Prefecture and Sado Island. In the first part of the article, we present …
Phase II study of preoperative sequential FEC and docetaxel predicts of pathological response and disease free survival
M Toi, S Nakamura, K Kuroi, H Iwata, S Ohno… - Breast cancer research …, 2008 - Springer
Purpose This multicenter phase II study examined the impact of pathological effect on
survival after preoperative chemotherapy in Japanese women with early stage breast …
survival after preoperative chemotherapy in Japanese women with early stage breast …
An epigenetic switch is crucial for spermatogonia to exit the undifferentiated state toward a Kit-positive identity
T Shirakawa, R Yaman-Deveci, S Tomizawa… - …, 2013 - journals.biologists.com
Epigenetic modifications influence gene expression and chromatin remodeling. In
embryonic pluripotent stem cells, these epigenetic modifications have been extensively …
embryonic pluripotent stem cells, these epigenetic modifications have been extensively …
[HTML][HTML] Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome
X Jia, T Yamamura, R Gbadegesin, MT McNulty… - Kidney international, 2020 - Elsevier
To understand the genetics of steroid-sensitive nephrotic syndrome (SSNS), we conducted a
genome-wide association study in 987 childhood SSNS patients and 3,206 healthy controls …
genome-wide association study in 987 childhood SSNS patients and 3,206 healthy controls …
[HTML][HTML] A randomized, double-blind, controlled study of exemestane versus anastrozole for the first-line treatment of postmenopausal Japanese women with hormone …
H Iwata, N Masuda, S Ohno, Y Rai, Y Sato… - Breast cancer research …, 2013 - Springer
The aromatase inhibitors exemestane and anastrozole are approved in Japan for first-line
treatment of postmenopausal patients with advanced, hormone-receptor-positive breast …
treatment of postmenopausal patients with advanced, hormone-receptor-positive breast …
Postoperative adjuvant anastrozole for 10 or 5 years in patients with hormone receptor–positive breast cancer: AERAS, a randomized multicenter open-label phase III …
T Iwase, S Saji, K Iijima, K Higaki… - Journal of Clinical …, 2023 - ingentaconnect.com
PURPOSE Treatment with an aromatase inhibitor for 5 years is the standard treatment for
postmenopausal hormone receptor–positive breast cancer. We investigated the effects of …
postmenopausal hormone receptor–positive breast cancer. We investigated the effects of …
Adjuvant S-1 plus endocrine therapy for oestrogen receptor-positive, HER2-negative, primary breast cancer: a multicentre, open-label, randomised, controlled, phase …
M Toi, S Imoto, T Ishida, Y Ito, H Iwata… - The Lancet …, 2021 - thelancet.com
Background Oral fluoropyrimidines, such as S-1, have been shown to have a role in
controlling disease progression in metastatic breast cancer. We examined adjuvant …
controlling disease progression in metastatic breast cancer. We examined adjuvant …
Shortened red blood cell lifespan is related to the dose of erythropoiesis‐stimulating agents requirement in patients on hemodialysis
Y Sato, T Mizuguchi, S Shigenaga… - Therapeutic …, 2012 - Wiley Online Library
Renal anemia is an important complication of chronic kidney disease (CKD). One of the
most important complications of renal anemia is reduced red blood cell (RBC) lifespan, but …
most important complications of renal anemia is reduced red blood cell (RBC) lifespan, but …
Periodically repeated rituximab administrations in children with refractory nephrotic syndrome: 2-year multicenter observational study
T Takahashi, T Okamoto, Y Sato, T Yamazaki… - Pediatric …, 2019 - Springer
Background Rituximab (RTX) is effective in maintaining remission in patients with nephrotic
syndrome (NS), but a standard protocol of RTX administration has not been established …
syndrome (NS), but a standard protocol of RTX administration has not been established …