Multiplex immunofluorescence (mIF) allows simultaneous antibody-based detection and
quantification of the expression of up to six markers, plus a nuclear counterstain, on a single …

Background and objective Intraoperative frozen section of the sentinel lymph node (SLN) in
clinically node negative breast cancer patients detects metastatic disease and enables …

Aims The presence of oestrogen and progesterone receptors (ER, PR) in breast carcinoma
is an important prognostic indicator as well as a predictor of likely response to hormonal …

Breast cancer is the most common malignancy in Singapore women. Ductal carcinoma in
situ (DCIS) is the putative, non-obligate precursor of the majority of invasive breast cancers …

Aim To identify important clinicopathological parameters that are most helpful in predicting
additional non-sentinel lymph node (SLN) metastasis among patients with a positive SLN …

Introduction We sought to assess the utility of the International System for Serous Fluid
Cytopathology (TIS) in the context of our department's routine practice. Materials and …

Aim We performed a retrospective review to determine the prognostic significance of
isolated tumour cells (ITCs) and micrometastases to the sentinel lymph nodes of patients …

Background Immunohistochemistry (IHC) and fluorescence in situ hybridisation (FISH) are
the only tests currently approved by the US Food and Drug Administration for classifying …

Proliferation of osteoclast-like giant cells in a cutaneous squamous cell carcinoma is a rare
phenomenon and so far only four cases have been reported. In previous reports, osteoclast …

Aim Phyllodes tumours (PTs) categorised as benign, borderline and malignant, account for
1% of all breast tumours. Histological assessment does not always predict tumour …