User profiles for "author:Sunit Das"
 | Sunit Das MD PhDSt. Michael's Hospital, University of Toronto Verified email at utoronto.ca Cited by 6873 |
Angiogenesis in glioblastoma
S Das, PA Marsden - New England Journal of Medicine, 2013 - Mass Medical Soc
Angiogenesis in Glioblastoma | NEJM Skip to main content NEJM Group Follow Us Facebook
Twitter Instagram YouTube LinkedIn Prepare to become a physician, build your knowledge …
Twitter Instagram YouTube LinkedIn Prepare to become a physician, build your knowledge …
IDH mutation in glioma: new insights and promises for the future
Z Turkalp, J Karamchandani, S Das - JAMA neurology, 2014 - jamanetwork.com
Importance Over the past 4 years, our understanding of gliomagenesis and the practice of
neuro-oncology have been radically changed by the discovery of mutations involving the …
neuro-oncology have been radically changed by the discovery of mutations involving the …
The incidence of brain metastases among patients with metastatic breast cancer: a systematic review and meta-analysis
Background Patients with metastatic breast cancer (MBC) are living longer, but the
development of brain metastases often limits their survival. We conducted a systematic …
development of brain metastases often limits their survival. We conducted a systematic …
Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy
Human glioblastomas harbour a subpopulation of glioblastoma stem cells that drive
tumorigenesis. However, the origin of intratumoural functional heterogeneity between …
tumorigenesis. However, the origin of intratumoural functional heterogeneity between …
Gradient of developmental and injury response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity
Glioblastomas harbor diverse cell populations, including rare glioblastoma stem cells
(GSCs) that drive tumorigenesis. To characterize functional diversity within this population …
(GSCs) that drive tumorigenesis. To characterize functional diversity within this population …
Single-cell multimodal glioma analyses identify epigenetic regulators of cellular plasticity and environmental stress response
KC Johnson, KJ Anderson, ET Courtois, AD Gujar… - Nature …, 2021 - nature.com
Glioma intratumoral heterogeneity enables adaptation to challenging microenvironments
and contributes to therapeutic resistance. We integrated 914 single-cell DNA methylomes …
and contributes to therapeutic resistance. We integrated 914 single-cell DNA methylomes …
[PDF][PDF] ASCL1 reorganizes chromatin to direct neuronal fate and suppress tumorigenicity of glioblastoma stem cells
Glioblastomas exhibit a hierarchical cellular organization, suggesting that they are driven by
neoplastic stem cells that retain partial yet abnormal differentiation potential. Here, we show …
neoplastic stem cells that retain partial yet abnormal differentiation potential. Here, we show …
[HTML][HTML] DNA hypermethylation within TERT promoter upregulates TERT expression in cancer
Replicative immortality is a hallmark of cancer cells governed by telomere maintenance.
Approximately 90% of human cancers maintain their telomeres by activating telomerase …
Approximately 90% of human cancers maintain their telomeres by activating telomerase …
[HTML][HTML] What do medical students actually need to know about artificial intelligence?
With emerging innovations in artificial intelligence (AI) poised to substantially impact medical
practice, interest in training current and future physicians about the technology is growing …
practice, interest in training current and future physicians about the technology is growing …
[HTML][HTML] PRMT5 inhibition disrupts splicing and stemness in glioblastoma
Glioblastoma (GBM) is a deadly cancer in which cancer stem cells (CSCs) sustain tumor
growth and contribute to therapeutic resistance. Protein arginine methyltransferase 5 …
growth and contribute to therapeutic resistance. Protein arginine methyltransferase 5 …