The targeting of antioxidant systems that allow stem-like cancer cells to avoid the adverse
consequences of oxidative stress might be expected to improve the efficacy of cancer …

Invasive dental treatment such as tooth extraction following treatment with strong anti-bone
resorptive agents, including bisphosphonates and denosumab, reportedly promotes …

Background Desmoid-type fibromatosis is defined as an intermediate tumor that rarely
occurs in the head and neck of children. There is no doubt as to the value of complete …

Introduction Osteonecrosis of the jaw (ONJ) occurring after invasive dental treatment often
adversely affects patients' activities of daily living. Long-term administration of strong anti …

Currently, implants are utilized clinically for bone transplant procedures. However, if
infectious osteomyelitis occurs at implant sites, removal of bacteria can be challenging …

Oral lichen planus is a chronic inflammatory mucocutaneous disease. Topical use of
steroids and other immuno-modulating therapies have been tried for this intractable …

Radical esophagectomy for thoracic esophageal cancer is invasive and frequently results in
postoperative pulmonary complications. Postoperative pneumonia is the most common such …

Objectives Immunotherapy with nivolumab for patients with recurrent/metastatic oral
squamous cell carcinoma has not been evaluated. Here, we aimed to examine the efficacy …

Introduction In early-stage oral tongue squamous cell carcinoma (OTSCC), elective neck
dissection (END) is recommended when occult lymph node metastasis is suspected; …

The oral cavity serves as the initial segment of the digestive system and is responsible for
both nutritional supplementation and the mechanical breakdown of food. It comprises …