The ontogeny of the human immune system is sensitive to nutrition even in the very early
embryo, with both deficiency and excess of macro-and micronutrients being potentially …

Background Trials done in infants with low birthweight in west Africa suggest that BCG
vaccination reduces all-cause mortality in the neonatal period, probably because of …

Introduction Prenatal exposures such as infections and immunisation may influence infant
responses. We had an opportunity to undertake an analysis of innate responses in infants …

Menarcheal age is a key indicator of female maturity and development. Studies in many
countries have reported a downward secular trend in age of menarche over the past century …

Undergraduate research has been shown to provide an exceptionally positive experience
for students (Seymour et al. 2004). In a study of student learning outcomes following …

Septicemia is a leading cause of death among neonates in low-income settings, a situation
that is deteriorating due to high levels of antimicrobial resistance. Novel interventions are …

Interest in the nonspecific effects of bacillus Calmette-Guérin (BCG) and the possibility that
BCG may provide protection against nonmycobacterial infectious disease has been growing …

Aims Clinical guidelines for management of infants with fever but no evident focus of
infection recommend that those aged 1–3 months with a white cell count> 15× 10 9/l have a …

Abstract Background The potential for Bacillus Calmette-Guérin (BCG) vaccination to protect
infants against non-mycobacterial disease has been suggested by a randomised controlled …

Abstract Bacillus Calmette-Guerin (BCG) vaccination has been reported to protect neonates
from non-tuberculous pathogens, but no biological mechanism to explain such effects is …