Simple Summary Angiosarcomas (AS) are rare, highly aggressive sarcomas with limited
therapeutic options. Genomic sequencing techniques have identified recurrent genetic …

Introduction: Giant bullous emphysema (GBE) is defined by giant bullae in one or both upper
lobes, occupying at least one-third of the hemithorax and compressing the surrounding …

Background Lacrimal gland adenoid cystic carcinoma (LGACC) has historically been
associated with a poor prognosis even with localized disease, with a survival of 56% at 5 …

Brentuximab vedotin (BV) is an antibody-drug conjugate composed of an anti-CD30
monoclonal antibody conjugated through a linker to the microtubule disturbing agent …

Background Studies suggest that surgical breast augmentation with implants is a risk factor
for breast desmoid tumors. The statistical strength of this correlation is unknown, as …

e21219 Background: Mutations in BRAF oncogene have been identified in about 2-4% of
non-small cell lung cancer (NSCLC) patients. Combination of tyrosine kinase inhibitors …

11514 Background: Tyrosine kinase inhibitors (TKIs) are the cornerstone treatment for
advanced GIST via pharmacologic targeting of driver oncogenes such as KIT. Detection of …

• Initial Comprehensive search yielded 2,618 studies. After excluding duplicates and those
that do not meet inclusion criteria, 34 studies were included in the final analysis. That brings …

Despite an initial response, most metastatic gastrointestinal stromal tumor (GIST) patients
will ultimately be refractory to all current therapies, including imatinib, sunitinib, and …

Introduction Ingestion of caustic materials can lead to digestive tube perforation involving the
mouth, pharynx, esophagus and stomach (Vezakis et al., 2016 [1]). In this case report, the …