User profiles for "author:Peter K Kim"
Peter K. KimHospital for Sick Children Verified email at sickkids.ca Cited by 23515 |
[HTML][HTML] WSES/GAIS/SIS-E/WSIS/AAST global clinical pathways for patients with intra-abdominal infections
M Sartelli, F Coccolini, Y Kluger, E Agastra… - World journal of …, 2021 - Springer
Intra-abdominal infections (IAIs) are common surgical emergencies and have been reported
as major contributors to non-trauma deaths in hospitals worldwide. The cornerstones of …
as major contributors to non-trauma deaths in hospitals worldwide. The cornerstones of …
[HTML][HTML] Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)
Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently
associated with poor prognosis, particularly in high-risk patients. The cornerstones in the …
associated with poor prognosis, particularly in high-risk patients. The cornerstones in the …
[HTML][HTML] 2019 update of the WSES guidelines for management of Clostridioides (Clostridium) difficile infection in surgical patients
In the last three decades, Clostridium difficile infection (CDI) has increased in incidence and
severity in many countries worldwide. The increase in CDI incidence has been particularly …
severity in many countries worldwide. The increase in CDI incidence has been particularly …
[HTML][HTML] Mitochondria supply membranes for autophagosome biogenesis during starvation
Starvation-induced autophagosomes engulf cytosol and/or organelles and deliver them to
lysosomes for degradation, thereby resupplying depleted nutrients. Despite advances in …
lysosomes for degradation, thereby resupplying depleted nutrients. Despite advances in …
NBR1 acts as an autophagy receptor for peroxisomes
E Deosaran, KB Larsen, R Hua… - Journal of cell …, 2013 - journals.biologists.com
Selective macro-autophagy is an intracellular process by which large cytoplasmic materials
are selectively sequestered and degraded in the lysosomes. Substrate selection is mediated …
are selectively sequestered and degraded in the lysosomes. Substrate selection is mediated …
ROS-induced mitochondrial depolarization initiates PARK2/PARKIN-dependent mitochondrial degradation by autophagy
Reactive oxygen species (ROS) have been implicated as a signal for general autophagy.
Both mitochondrial-produced and exogenous ROS induce autophagosome formation …
Both mitochondrial-produced and exogenous ROS induce autophagosome formation …
The origin and maintenance of mammalian peroxisomes involves a de novo PEX16-dependent pathway from the ER
Peroxisomes are ubiquitous organelles that proliferate under different physiological
conditions and can form de novo in cells that lack them. The endoplasmic reticulum (ER) has …
conditions and can form de novo in cells that lack them. The endoplasmic reticulum (ER) has …
Assessment of physician sleep and wellness, burnout, and clinically significant medical errors
Importance Sleep-related impairment in physicians is an occupational hazard associated
with long and sometimes unpredictable work hours and may contribute to burnout and self …
with long and sometimes unpredictable work hours and may contribute to burnout and self …
[HTML][HTML] Regulated intramembrane proteolysis of the p75 neurotrophin receptor modulates its association with the TrkA receptor
KM Jung, S Tan, N Landman, K Petrova… - Journal of Biological …, 2003 - ASBMB
The generation of biologically active proteins by regulated intramembrane proteolysis is a
highly conserved mechanism in cell signaling. Presenilin-dependent γ-secretase activity is …
highly conserved mechanism in cell signaling. Presenilin-dependent γ-secretase activity is …
VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis
Lipid exchange between the endoplasmic reticulum (ER) and peroxisomes is necessary for
the synthesis and catabolism of lipids, the trafficking of cholesterol, and peroxisome …
the synthesis and catabolism of lipids, the trafficking of cholesterol, and peroxisome …