Right heart adaptation to pulmonary arterial hypertension: physiology and pathobiology

A Vonk-Noordegraaf, F Haddad, KM Chin… - Journal of the American …, 2013 - jacc.org
Survival in patients with pulmonary arterial hypertension (PAH) is closely related to right
ventricular (RV) function. Although pulmonary load is an important determinant of RV …

Tricuspid annular displacement predicts survival in pulmonary hypertension

PR Forfia, MR Fisher, SC Mathai… - American journal of …, 2006 - atsjournals.org
Rationale: Right ventricular (RV) function is an important determinant of prognosis in
pulmonary hypertension. However, noninvasive assessment of the RV function is often …

Accuracy of Doppler echocardiography in the hemodynamic assessment of pulmonary hypertension

MR Fisher, PR Forfia, E Chamera… - American journal of …, 2009 - atsjournals.org
Rationale: Transthoracic Doppler echocardiography is recommended for screening for the
presence of pulmonary hypertension (PH). However, some recent studies have suggested …

Diagnosis and assessment of pulmonary vascular disease by Doppler echocardiography

JD Roberts, PR Forfia - Pulmonary Circulation, 2011 - journals.sagepub.com
Pulmonary hypertension (PH) is a relatively misunderstood disease, partly related to the fact
that many perceive PH to be a singular diagnosis. An unintended consequence of this is the …

Pulmonary heart disease: The heart-lung interaction and its impact on patient phenotypes

PR Forfia, A Vaidya, SE Wiegers - Pulmonary circulation, 2013 - journals.sagepub.com
Pulmonary heart disease (PHD) refers to altered structure or function of the right ventricle
occurring in association with abnormal respiratory function. Although nearly always …

Right ventricular function in heart failure with preserved ejection fraction: a community-based study

SF Mohammed, I Hussain, OF AbouEzzeddine… - Circulation, 2014 - Am Heart Assoc
Background—The prevalence and clinical significance of right ventricular (RV) systolic
dysfunction (RVD) in patients with heart failure and preserved ejection fraction (HFpEF) are …

Relationship between B-type natriuretic peptides and pulmonary capillary wedge pressure in the intensive care unit

PR Forfia, SP Watkins, JE Rame, KJ Stewart… - Journal of the American …, 2005 - jacc.org
Objectives: We examined whether B-type natriuretic peptides (BNP) can serve as
noninvasive markers of pulmonary capillary wedge pressure (PCWP) in the setting of critical …

Shape of the right ventricular Doppler envelope predicts hemodynamics and right heart function in pulmonary hypertension

JS Arkles, AR Opotowsky, J Ojeda… - American journal of …, 2011 - atsjournals.org
Rationale: Systolic deceleration or “notching” of the right ventricular outflow tract Doppler
flow velocity envelope (FVERVOT) relates to pathologic wave reflection in the setting of …

Hyponatremia predicts right heart failure and poor survival in pulmonary arterial hypertension

PR Forfia, SC Mathai, MR Fisher… - American journal of …, 2008 - atsjournals.org
Rationale: Hyponatremia is associated with decompensated heart failure and poor
prognosis in patients with left ventricular systolic dysfunction. Objectives: We sought to …

Longitudinal shortening accounts for the majority of right ventricular contraction and improves after pulmonary vasodilator therapy in normal subjects and patients with …

SB Brown, A Raina, D Katz, M Szerlip, SE Wiegers… - Chest, 2011 - Elsevier
Background The right ventricle has a unique contraction pattern, with a greater portion of the
shortening occurring in the longitudinal plane. However, the relative contributions of …