The obese (ob) gene, the mutation of which results in severe hereditary obesity and
diabetes in mice, has recently been isolated through positional cloning. In this study, we …

The obese (ob) gene has been identified through a positional cloning approach; the
mutation of this gene causes marked hereditary obesity and diabetes mellitus in mice. We …

We cloned the full-length rat leptin receptor (Ob-R) isoform complementary DNAs (cDNAs)
and examined the gene expression in rats. We also identified a mutation in Ob-R in Zucker …

The obese (ob) gene has recently been isolated through a positional cloning approach, the
mutation of which causes a marked hereditary obesity and diabetes mellitus in mice. In the …

Prostacyclin receptor is a member of the prostanoid receptor family in the G protein-coupled
receptor superfamily with seven transmembrane domains. We report here the isolation and …

We have isolated and characterized the mouse adrenomedullin (AM) gene (Adm) and
determined its chromosomal location. The gene spans approximately 2.1 kb and is …

Leptin is an adipocyte-derived blood-borne satiety factor that is involved in the regulation of
energy homeostasis. We have recently demonstrated nonadipose tissue production of …

Introduction Granulomatosis with polyangiitis is a systemic inflammatory disease that often
presents with necrosis, granuloma formation and vasculitis of small-to medium-sized …

A 72-year-old Japanese man treated with omeprazole for 11 years was admitted due to loss
of consciousness and muscle weakness. Wolff-Parkinson-White syndrome-induced …

Background: Smoking relapse prevention after completion of a smoking cessation program
is highly germane to reducing smoking rates. Objective: The purpose of this study was to …