Isatuximab, carfilzomib, and dexamethasone in relapsed multiple myeloma (IKEMA): a multicentre, open-label, randomised phase 3 trial
Background Isatuximab is an anti-CD38 monoclonal antibody approved in combination with
pomalidomide–dexamethasone and carfilzomib–dexamethasone for relapsed or refractory …
pomalidomide–dexamethasone and carfilzomib–dexamethasone for relapsed or refractory …
Isatuximab plus pomalidomide and low-dose dexamethasone versus pomalidomide and low-dose dexamethasone in patients with relapsed and refractory multiple …
M Attal, PG Richardson, SV Rajkumar, J San-Miguel… - The Lancet, 2019 - thelancet.com
Background Isatuximab is a monoclonal antibody that binds a specific epitope on the human
CD38 receptor and has antitumour activity via multiple mechanisms of action. In a previous …
CD38 receptor and has antitumour activity via multiple mechanisms of action. In a previous …
Comparative single-institute analysis of cord blood transplantation from unrelated donors with bone marrow or peripheral blood stem-cell transplants from related …
S Takahashi, J Ooi, A Tomonari, T Konuma, N Tsukada… - Blood, 2007 - ashpublications.org
We studied the clinical outcomes of 171 adults with hematologic malignancies who received
unrelated cord blood transplantation (CBT) as a primary unrelated stem-cell source (n …
unrelated cord blood transplantation (CBT) as a primary unrelated stem-cell source (n …
Oral Iptacopan Monotherapy in Paroxysmal Nocturnal Hemoglobinuria
R Peffault de Latour, A Röth… - … England Journal of …, 2024 - Mass Medical Soc
Background Persistent hemolytic anemia and a lack of oral treatments are challenges for
patients with paroxysmal nocturnal hemoglobinuria who have received anti-C5 therapy or …
patients with paroxysmal nocturnal hemoglobinuria who have received anti-C5 therapy or …
Factor B Inhibition with Oral Iptacopan Monotherapy Demonstrates Sustained Long-Term Efficacy and Safety in Anti-C5-Treated Patients (pts) with Paroxysmal …
AM Risitano, A Kulasekararaj, A Roeth, P Scheinberg… - Blood, 2023 - Elsevier
Drs Roeth and Kulasekararaj contributed equally as authors. Background: Iptacopan is the
first oral complement inhibitor that acts proximally in the complement system to target factor …
first oral complement inhibitor that acts proximally in the complement system to target factor …
[HTML][HTML] Case report of subcutaneous panniculitis-like T-cell lymphoma complicated by eyelid swelling
R Hashimoto, M Uchiyama, T Maeno - BMC ophthalmology, 2016 - Springer
Background Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare, highly
malignant, extranodal lymphoma that preferentially infiltrates into subcutaneous adipose …
malignant, extranodal lymphoma that preferentially infiltrates into subcutaneous adipose …
EMD originates from hyaluronan-induced homophilic interactions of CD44 variant-expressing MM cells under shear stress
J Kikuchi, N Kodama, M Takeshita, S Ikeda… - Blood …, 2023 - ashpublications.org
Extramedullary disease (EMD) is known to be associated with chemoresistance and poor
prognosis in multiple myeloma (MM); however, the mechanisms of its development are not …
prognosis in multiple myeloma (MM); however, the mechanisms of its development are not …
Isatuximab monotherapy in relapsed/refractory multiple myeloma: A Japanese, multicenter, phase 1/2, safety and efficacy study
K Sunami, K Suzuki, M Ri, M Matsumoto… - Cancer …, 2020 - Wiley Online Library
Isatuximab, an anti‐CD38 monoclonal antibody, targets cells that strongly express CD38
including malignant plasma cells. This open‐label, single‐arm, multicenter, phase 1/2 trial …
including malignant plasma cells. This open‐label, single‐arm, multicenter, phase 1/2 trial …
Human herpesvirus 6 variant B infection in adult patients after unrelated cord blood transplantation
A Tomonari, S Takahashi, J Ooi, T Iseki… - International journal of …, 2005 - Springer
Human herpesvirus 6 var1iant B (HHV-6B) infection was studied in 23 adult patients who
underwent cord blood transplantation (CBT). HHV-6B DNA was detected by quantitative …
underwent cord blood transplantation (CBT). HHV-6B DNA was detected by quantitative …
Pulmonary alveolar proteinosis in a patient with Behcet's disease
M Uchiyama, T Nagao, A Hattori, T Fujii… - …, 2009 - Wiley Online Library
Secondary pulmonary alveolar proteinosis (PAP) has been described in several clinical
settings that can be grouped into three main categories: infections of the lung; …
settings that can be grouped into three main categories: infections of the lung; …