[HTML][HTML] Dysregulated naive B cells and de novo autoreactivity in severe COVID-19
MC Woodruff, RP Ramonell, NS Haddad, FA Anam… - Nature, 2022 - nature.com
Severe SARS-CoV-2 infection has been associated with highly inflammatory immune
activation since the earliest days of the COVID-19 pandemic,,–. More recently, these …
activation since the earliest days of the COVID-19 pandemic,,–. More recently, these …
Intervertebral disc injury complicating cervical spine trauma
SJ RIZZOLO, MR PIAZZA, JM COTLER… - Spine, 1991 - journals.lww.com
The incidence of acute herniated nucleus pulposus was determined in 55 patients with
cervical spine trauma. A standardized protocol and a 1.5-T magnetic resonance image …
cervical spine trauma. A standardized protocol and a 1.5-T magnetic resonance image …
Changes in cardiovascular calcification after parathyroidectomy in patients with ESRD
AJ Bleyer, J Burkart, M Piazza, G Russell… - American Journal of …, 2005 - Elsevier
Background: The effect of parathyroidectomy on vascular calcification in patients with end-
stage renal disease has been a subject of interest for many years, although studies in this …
stage renal disease has been a subject of interest for many years, although studies in this …
Relaxed peripheral tolerance drives broad de novo autoreactivity in severe COVID-19
An emerging feature of COVID-19 is the identification of autoreactivity in patients with severe
disease that may contribute to disease pathology, however the origin and resolution of these …
disease that may contribute to disease pathology, however the origin and resolution of these …
Structural consequences of calmodulin EF hand mutations
M Piazza, V Taiakina, T Dieckmann… - Biochemistry, 2017 - ACS Publications
Calmodulin (CaM) is a cytosolic Ca2+-binding protein that serves as a control element for
many enzymes. It consists of two globular domains, each containing two EF hand pairs …
many enzymes. It consists of two globular domains, each containing two EF hand pairs …
Structure and dynamics of calmodulin (CaM) bound to nitric oxide synthase peptides: effects of a phosphomimetic CaM mutation
Nitric oxide synthase (NOS) plays a major role in a number of key physiological and
pathological processes. Knowledge of how this is regulated is important. The small acidic …
pathological processes. Knowledge of how this is regulated is important. The small acidic …
Dynamics of nitric oxide synthase–calmodulin interactions at physiological calcium concentrations
M Piazza, JG Guillemette, T Dieckmann - Biochemistry, 2015 - ACS Publications
The intracellular Ca2+ concentration is an important regulator of many cellular functions.
The small acidic protein calmodulin (CaM) serves as a Ca2+ sensor and control element for …
The small acidic protein calmodulin (CaM) serves as a Ca2+ sensor and control element for …
[HTML][HTML] Calmodulin regulates Cav3 T-type channels at their gating brake
Calcium (Ca v 1 and Ca v 2) and sodium channels possess homologous CaM-binding
motifs, known as IQ motifs in their C termini, which associate with calmodulin (CaM), a …
motifs, known as IQ motifs in their C termini, which associate with calmodulin (CaM), a …
Structural studies of a complex between endothelial nitric oxide synthase and calmodulin at physiological calcium concentration
M Piazza, T Dieckmann, JG Guillemette - Biochemistry, 2016 - ACS Publications
The small acidic protein calmodulin (CaM) serves as a Ca2+ sensor and control element for
many enzymes including nitric oxide synthase (NOS) enzymes that play major roles in key …
many enzymes including nitric oxide synthase (NOS) enzymes that play major roles in key …
Solution structure of calmodulin bound to the target peptide of endothelial nitric oxide synthase phosphorylated at Thr495
M Piazza, V Taiakina, SR Guillemette… - Biochemistry, 2014 - ACS Publications
Nitric oxide synthase (NOS) plays a major role in a number of key physiological and
pathological processes, and it is important to understand how this enzyme is regulated. The …
pathological processes, and it is important to understand how this enzyme is regulated. The …