User profiles for "author:Mahesh Choolani"

Mahesh Choolani

National University of Singapore NUS/NUH/NUHS
Verified email at nus.edu.sg
Cited by 13804

Coronavirus disease 2019 (COVID-19) pandemic and pregnancy

P Dashraath, JLJ Wong, MXK Lim, LM Lim, S Li… - American journal of …, 2020 - Elsevier
The current coronavirus disease 2019 (COVID-19) pneumonia pandemic, caused by the
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is spreading globally at an …

The potential of human fetal mesenchymal stem cells for off-the-shelf bone tissue engineering application

ZY Zhang, SH Teoh, JHP Hui, NM Fisk, M Choolani… - Biomaterials, 2012 - Elsevier
Mesenchymal stem cells (MSCs) have become one of the most promising cell sources for
bone tissue engineering (BTE) applications. In this review, we first highlight recent progress …

Mechanisms and evidence of vertical transmission of infections in pregnancy including SARS‐CoV‐2s

AP Mahyuddin, A Kanneganti, JJL Wong… - Prenatal …, 2020 - Wiley Online Library
There remain unanswered questions concerning mother‐to‐child‐transmission of SARS‐
CoV‐2. Despite reports of neonatal COVID‐19, SARS‐CoV‐2 has not been consistently …

[PDF][PDF] Unsupervised high-dimensional analysis aligns dendritic cells across tissues and species

M Guilliams, CA Dutertre, CL Scott, N McGovern… - Immunity, 2016 - cell.com
Dendritic cells (DCs) are professional antigen-presenting cells that hold great therapeutic
potential. Multiple DC subsets have been described, and it remains challenging to align …

Superior osteogenic capacity for bone tissue engineering of fetal compared with perinatal and adult mesenchymal stem cells

ZY Zhang, SH Teoh, MSK Chong, JT Schantz… - Stem …, 2009 - academic.oup.com
Mesenchymal stem cells (MSCs) from human adult bone marrow (haMSCs) represent a
promising source for bone tissue engineering. However, their low frequencies and limited …

[PDF][PDF] Microbial exposure during early human development primes fetal immune cells

A Mishra, GC Lai, LJ Yao, TT Aung, N Shental… - Cell, 2021 - cell.com
The human fetal immune system begins to develop early during gestation; however, factors
responsible for fetal immune-priming remain elusive. We explored potential exposure to …

A study on Singaporean women's acceptance of using mobile phones to seek health information

S Lim, L Xue, CC Yen, L Chang, HC Chan… - International journal of …, 2011 - Elsevier
OBJECTIVE: This paper is an exploratory study that investigates Singaporean women's
acceptance of using mobile phones to seek health information. METHOD: A mobile web …

Care of the pregnant woman with coronavirus disease 2019 in labor and delivery: anesthesia, emergency cesarean delivery, differential diagnosis in the acutely ill …

B Ashokka, MH Loh, CH Tan, LL Su, BE Young… - American journal of …, 2020 - Elsevier
Coronavirus disease 2019, caused by the severe acute respiratory syndrome coronavirus 2,
has been declared a pandemic by the World Health Organization. As the pandemic evolves …

Human fetal dendritic cells promote prenatal T-cell immune suppression through arginase-2

N McGovern, A Shin, G Low, D Low, K Duan, LJ Yao… - Nature, 2017 - nature.com
During gestation the developing human fetus is exposed to a diverse range of potentially
immune-stimulatory molecules including semi-allogeneic antigens from maternal cells …

Identification of nestin-positive putative mammary stem cells in human breastmilk

MD Cregan, Y Fan, A Appelbee, ML Brown… - Cell and tissue …, 2007 - Springer
Stem cells in mammary tissue have been well characterised by using the mammary stem
cell marker, cytokeratin (CK) 5 and the mature epithelial markers CK14, CK18 and CK19. As …