User profiles for "author:Leonardo Pasalic"

Leonardo Pasalic

Clinical Senior Lecturer, University of Sydney
Verified email at sydney.edu.au
Cited by 2091

Laboratory tests used to help diagnose von Willebrand disease: an update

EJ Favaloro, L Pasalic, J Curnow - Pathology, 2016 - Elsevier
Summary von Willebrand disease (VWD) is due to quantitative deficiencies and/or
qualitative defects in von Willebrand factor (VWF), and is reportedly the most common …

[HTML][HTML] Platelets in coronavirus disease 2019

JB Larsen, L Pasalic, AM Hvas - Seminars in thrombosis and …, 2020 - thieme-connect.com
In December 2019, the first cases of infection with a novel human microorganism, now
officially defined as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), were …

[HTML][HTML] Review and evolution of guidelines for diagnosis of COVID-19 vaccine induced thrombotic thrombocytopenia (VITT)

EJ Favaloro, L Pasalic, G Lippi - Clinical Chemistry and Laboratory …, 2022 - degruyter.com
Abstract Coronavirus disease 2019 (COVID-19) is a life-threatening infectious disease
caused by Severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2). In response to …

The effect of the direct factor Xa inhibitors apixaban and rivaroxaban on haemostasis tests: a comprehensive assessment using in vitro and ex vivo samples

R Bonar, EJ Favaloro, S Mohammed, M Ahuja… - Pathology, 2016 - Elsevier
The direct oral anticoagulants (DOACs), now including dabigatran, apixaban and
rivaroxaban, have given clinicians alternative options to low molecular weight heparins …

Necrotic platelets provide a procoagulant surface during thrombosis

VM Hua, L Abeynaike, E Glaros… - Blood, The Journal …, 2015 - ashpublications.org
A subpopulation of platelets fulfills a procoagulant role in hemostasis and thrombosis by
enabling the thrombin burst required for fibrin formation and clot stability at the site of …

Therapeutic monitoring of unfractionated heparin–trials and tribulations

I Baluwala, EJ Favaloro, L Pasalic - Expert Review of Hematology, 2017 - Taylor & Francis
Introduction: Heparin is one of the oldest biological medicines with an established role in
prevention and treatment of arterial and venous thromboembolism. Published therapeutic …

[HTML][HTML] Lupus anticoagulant testing during anticoagulation, including direct oral anticoagulants

EJ Favaloro, L Pasalic - Research and practice in thrombosis and …, 2022 - Elsevier
Background Lupus anticoagulants (LA) are one laboratory criterion for classification of
antiphospholipid syndrome, with presence of vascular thrombosis and/or pregnancy/fetal …

Laboratory testing for lupus anticoagulant (LA) in patients taking direct oral anticoagulants (DOACs): potential for false positives and false negatives

EJ Favaloro, S Mohammed, J Curnow, L Pasalic - Pathology, 2019 - Elsevier
We and others have previously highlighted the potential problems with testing of lupus
anticoagulants (LA) in patients on anticoagulant therapy, including most recently as related …

Treatment of von Willebrand disease

J Curnow, L Pasalic, EJ Favaloro - Seminars in Thrombosis …, 2016 - thieme-connect.com
Congenital von Willebrand disease (VWD) and acquired von Willebrand syndrome (AVWS)
reflect conditions caused by von Willebrand factor (VWF) deficiency and/or defects. VWD is …

Laboratory testing for ADAMTS13: utility for TTP diagnosis/exclusion and beyond

EJ Favaloro, L Pasalic, B Henry… - American journal of …, 2021 - Wiley Online Library
The metalloproteinase ADAMTS13 (a disintegrin with a thrombospondin type 1 motif,
member 13), also known as VWF (von Willebrand factor) protease, may be assessed in a …