User profiles for "author:Julian Gunn"
Julian GunnProfessor of Interventional Cardiology, University of Sheffield Verified email at sheffield.ac.uk Cited by 7953 |
[HTML][HTML] Computational fluid dynamics modelling in cardiovascular medicine
PD Morris, A Narracott, H von Tengg-Kobligk… - Heart, 2016 - heart.bmj.com
This paper reviews the methods, benefits and challenges associated with the adoption and
translation of computational fluid dynamics (CFD) modelling within cardiovascular medicine …
translation of computational fluid dynamics (CFD) modelling within cardiovascular medicine …
[PDF][PDF] Coronary stents: historical development, current status and future directions.
Coronary artery disease (CAD) is the leading cause of morbidity and mortality in the world.
Central to the pathogenesis of CAD is the development of atherosclerotic lesions in coronary …
Central to the pathogenesis of CAD is the development of atherosclerotic lesions in coronary …
A collaborative systematic review and meta-analysis on 1278 patients undergoing percutaneous drug-eluting stenting for unprotected left main coronary artery …
BACKGROUND: Cardiac surgery is the standard treatment for unprotected left main disease
(ULM). Drug-eluting stent (DES) implantation has been recently reported in patients with …
(ULM). Drug-eluting stent (DES) implantation has been recently reported in patients with …
Virtual fractional flow reserve from coronary angiography: modeling the significance of coronary lesions: results from the VIRTU-1 (VIRTUal Fractional Flow Reserve …
PD Morris, D Ryan, AC Morton, R Lycett… - JACC: Cardiovascular …, 2013 - jacc.org
Objectives: The aim of this study was to develop a computer model that accurately predicts
myocardial fractional flow reserve (FFR) from angiographic images alone, in patients with …
myocardial fractional flow reserve (FFR) from angiographic images alone, in patients with …
The effect of interleukin-1 receptor antagonist therapy on markers of inflammation in non-ST elevation acute coronary syndromes: the MRC-ILA Heart Study
AC Morton, AMK Rothman, JP Greenwood… - European heart …, 2015 - academic.oup.com
Abstract Aims Acute coronary syndromes (ACSs) are driven by inflammation within coronary
plaque. Interleukin-1 (IL-1) has an established role in atherogenesis and the vessel …
plaque. Interleukin-1 (IL-1) has an established role in atherogenesis and the vessel …
Interleukin-1 receptor antagonist gene polymorphism and coronary artery disease
Background—Cytokine gene variations are contributory factors in inflammatory pathology.
Allele frequencies of interleukin (IL)-1 cluster genes [IL-1A (-889), IL-1B (-511), IL-1B (+ …
Allele frequencies of interleukin (IL)-1 cluster genes [IL-1A (-889), IL-1B (-511), IL-1B (+ …
Optimal medical therapy improves clinical outcomes in patients undergoing revascularization with percutaneous coronary intervention or coronary artery bypass …
J Iqbal, YJ Zhang, DR Holmes, MC Morice, MJ Mack… - Circulation, 2015 - Am Heart Assoc
Background—There is a paucity of data on the use of optimal medical therapy (OMT) in
patients with complex coronary artery disease undergoing revascularization with …
patients with complex coronary artery disease undergoing revascularization with …
“Virtual”(computed) fractional flow reserve: current challenges and limitations
PD Morris, FN van de Vosse, PV Lawford… - JACC: Cardiovascular …, 2015 - jacc.org
Fractional flow reserve (FFR) is the “gold standard” for assessing the physiological
significance of coronary artery disease during invasive coronary angiography. FFR-guided …
significance of coronary artery disease during invasive coronary angiography. FFR-guided …
The influence of physical stent parameters upon restenosis
AC Morton, D Crossman, J Gunn - Pathologie Biologie, 2004 - Elsevier
In this paper we examine whether the structure, geometry and dimensions of coronary stents
influence the occurrence of restenosis. Whilst many consider these parameters to be less …
influence the occurrence of restenosis. Whilst many consider these parameters to be less …
The effects of stenting on shear stress: relevance to endothelial injury and repair
K Van der Heiden, FJH Gijsen, A Narracott… - Cardiovascular …, 2013 - academic.oup.com
Stent deployment following balloon angioplasty is used routinely to treat coronary artery
disease. These interventions cause damage and loss of endothelial cells (EC), and thus …
disease. These interventions cause damage and loss of endothelial cells (EC), and thus …