Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages
The histiocytoses are rare disorders characterized by the accumulation of macrophage,
dendritic cell, or monocyte-derived cells in various tissues and organs of children and adults …
dendritic cell, or monocyte-derived cells in various tissues and organs of children and adults …
Consensus recommendations for the diagnosis and clinical management of Rosai-Dorfman-Destombes disease
O Abla, E Jacobsen, J Picarsic… - Blood, The Journal …, 2018 - ashpublications.org
Abstract Rosai-Dorfman-Destombes disease (RDD) is a rare non–Langerhans cell
histiocytosis characterized by accumulation of activated histiocytes within affected tissues …
histiocytosis characterized by accumulation of activated histiocytes within affected tissues …
[HTML][HTML] Congenital neutropenia: diagnosis, molecular bases and patient management
J Donadieu, O Fenneteau, B Beaupain… - Orphanet journal of rare …, 2011 - Springer
The term congenital neutropenia encompasses a family of neutropenic disorders, both
permanent and intermittent, severe (< 0.5 G/l) or mild (between 0.5-1.5 G/l), which may also …
permanent and intermittent, severe (< 0.5 G/l) or mild (between 0.5-1.5 G/l), which may also …
B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen
Neutrophils use immunoglobulins to clear antigen, but their role in immunoglobulin
production is unknown. Here we identified neutrophils around the marginal zone (MZ) of the …
production is unknown. Here we identified neutrophils around the marginal zone (MZ) of the …
High prevalence of BRAF V600E mutations in Erdheim-Chester disease but not in other non-Langerhans cell histiocytoses
J Haroche, F Charlotte, L Arnaud… - Blood, The Journal …, 2012 - ashpublications.org
Histiocytoses are rare disorders of unknown origin with highly heterogeneous prognosis.
BRAF mutations have been observed in Langerhans cell histiocytosis (LCH). We …
BRAF mutations have been observed in Langerhans cell histiocytosis (LCH). We …
Dramatic efficacy of vemurafenib in both multisystemic and refractory Erdheim-Chester disease and Langerhans cell histiocytosis harboring the BRAF V600E …
J Haroche, F Cohen-Aubart, JF Emile… - Blood, The Journal …, 2013 - ashpublications.org
Histiocytoses are rare disorders of unknown origin with highly heterogeneous prognosis.
BRAFV600E gain-of-function mutations have been observed in 57% of cases of Langerhans …
BRAFV600E gain-of-function mutations have been observed in 57% of cases of Langerhans …
Langerhans cell histiocytosis (LCH): guidelines for diagnosis, clinical work‐up, and treatment for patients till the age of 18 years
These guidelines for the management of patients up to 18 years with Langerhans cell
histiocytosis (LCH) have been set up by a group of experts involved in the Euro Histio Net …
histiocytosis (LCH) have been set up by a group of experts involved in the Euro Histio Net …
Diverse and targetable kinase alterations drive histiocytic neoplasms
EL Diamond, BH Durham, J Haroche, Z Yao, J Ma… - Cancer discovery, 2016 - AACR
Histiocytic neoplasms are clonal, hematopoietic disorders characterized by an accumulation
of abnormal, monocyte-derived dendritic cells or macrophages in Langerhans cell …
of abnormal, monocyte-derived dendritic cells or macrophages in Langerhans cell …
The European Society for Immunodeficiencies (ESID) registry working definitions for the clinical diagnosis of inborn errors of immunity
Patient registries are instrumental for clinical research in rare diseases. They help to achieve
a sufficient sample size for epidemiological and clinical research and to assess the …
a sufficient sample size for epidemiological and clinical research and to assess the …
Autoimmune and inflammatory manifestations occur frequently in patients with primary immunodeficiencies
A Fischer, J Provot, JP Jais, A Alcais… - Journal of Allergy and …, 2017 - Elsevier
Background Primary immunodeficiencies (PIDs) are inherited diseases associated with a
considerable increase in susceptibility to infections. It is known that PIDs can also …
considerable increase in susceptibility to infections. It is known that PIDs can also …