[HTML][HTML] Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts

A Rakovic, A Grünewald, J Kottwitz, N Brüggemann… - PloS one, 2011 - journals.plos.org
PINK1 and Parkin mutations cause recessive Parkinson's disease (PD). In Drosophila and
SH-SY5Y cells, Parkin is recruited by PINK1 to damaged mitochondria, where it …

[HTML][HTML] A novel circulating noncoding small RNA for the detection of acute myocarditis

R Blanco-Domínguez, R Sánchez-Díaz… - … England Journal of …, 2021 - Mass Medical Soc
Background The diagnosis of acute myocarditis typically requires either endomyocardial
biopsy (which is invasive) or cardiovascular magnetic resonance imaging (which is not …

Cardiac magnetic resonance imaging in myocarditis reveals persistent disease activity despite normalization of cardiac enzymes and inflammatory parameters at 3 …

J Berg, J Kottwitz, N Baltensperger… - Circulation: Heart …, 2017 - Am Heart Assoc
Background: There is a major unmet need to identify high-risk patients in myocarditis.
Although decreasing cardiac and inflammatory markers are commonly interpreted as …

Update on myocarditis–what we know so far and where we may be heading

A Rroku, J Kottwitz, B Heidecker - European Heart Journal Acute …, 2021 - academic.oup.com
Myocarditis is defined as an inflammatory infiltration of the myocardium with associated
necrosis and/or degeneration, frequently resulting from different infectious or non-infectious …

Non-steroidal anti-inflammatory drug use in acute myopericarditis: 12-month clinical follow-up

J Berg, M Lovrinovic, N Baltensperger, CK Kissel… - Open …, 2019 - openheart.bmj.com
Objective Clinical data on the effect of non-steroidal anti-inflammatory drugs (NSAIDs) in
myopericarditis are limited. Since NSAIDs are standard therapy in pericarditis, we …

Systematic use of cardiac magnetic resonance imaging in MINOCA led to a five-fold increase in the detection rate of myocarditis: a retrospective study

B Heidecker, G Ruedi, N Baltensperger… - Swiss medical …, 2019 - zora.uzh.ch
BACKGROUND Systematic work-up of patients with myocardial infarction and non-
obstructive coronary artery disease (MINOCA) using cardiac magnetic resonance imaging …

Clinical presentation and laboratory findings in men versus women with myocarditis

D Patriki, J Kottwitz, J Berg, U Landmesser… - Journal of women's …, 2020 - liebertpub.com
Objectives: Understanding sex differences in myocarditis is crucial to improve clinical care.
We sought to investigate sex differences focusing on clinical presentation and laboratory …

Virome sequencing in patients with myocarditis

B Heidecker, SH Williams, K Jain, A Oleynik… - Circulation: Heart …, 2020 - Am Heart Assoc
Background: Polymerase chain reaction analyses of cardiac tissues have detected viral
sequences in up to 67% of cases of myocarditis. However, viruses have not been implicated …

[PDF][PDF] FIMICS: a panel of long noncoding RNAs for cardiovascular conditions

H Firat, L Zhang, S Baksi, P Leszek, E Schordan… - Heliyon, 2023 - cell.com
Cardiovascular disorders such as heart failure are leading causes of mortality. Patient
stratification via identification of novel biomarkers could improve management of …

[HTML][HTML] Myoglobin for detection of high-risk patients with acute myocarditis

J Kottwitz, KA Bruno, J Berg, GR Salomon… - Journal of …, 2020 - Springer
There is an unmet need for accurate and practical screening to detect myocarditis. We
sought to test the hypothesis that the extent of acute myocarditis, measured by late …