[HTML][HTML] The role of complement in kidney disease

J Willows, M Brown, NS Sheerin - Clinical Medicine, 2020 - ncbi.nlm.nih.gov
While the complement cascade is an important component of the innate immune system,
uncontrolled activation can cause severe disease. This concept is illustrated by the …

The challenges of diagnosis and management of Gitelman syndrome

S Urwin, J Willows, JA Sayer - Clinical Endocrinology, 2020 - Wiley Online Library
Gitelman syndrome is an inherited tubulopathy characterized by renal salt wasting from the
distal convoluted tubule. Defects in the sodium chloride cotransporter (encoded by …

Acute interstitial nephritis due to sodium-glucose co-transporter 2 inhibitor empagliflozin

R Ryan, S Choo, J Willows, J Walker… - Clinical Kidney …, 2021 - academic.oup.com
Biopsy-proven acute interstitial nephritis (AIN) secondary to sodium-glucose co-transporter 2
(SGLT2) inhibitors has not been described previously. Here, we report on the management …

[HTML][HTML] Case report: investigation and molecular genetic diagnosis of familial hypomagnesaemia

J Willows, M Al Badi, C Richardson, A Al Sinani… - …, 2019 - ncbi.nlm.nih.gov
Genetic mutations causing familial hypomagnesaemia syndromes are well-recognised.
Affected patients can present with severe symptoms of hypomagnesaemia, such as seizures …

Seasonal hypercalcaemia; consider CYP24A1 mutation

J Willows, JA Sayer - QJM: An International Journal of Medicine, 2019 - academic.oup.com
Dear Editor, We read with interest the case report entitled 'Seasonal Hypercalcaemia'. 1 We
wish to congratulate the authors on reporting this interesting case, and hoped to make some …

Use of Terlipressin in AKI Associated Hepatorenal Syndrome: CON

J Willows, S Hiremath - Kidney360, 2024 - journals.lww.com
Disclosures: ASN journals have adopted the ASN Conflict of Interest and Disclosure Policy,
available here. In summary, authors should disclose any financial relationships or …

changing protein permeability with nephron loss: Evidence for a human remnant nephron effect

J Willows, A Odudu, I Logan, N Sheerin… - American Journal of …, 2019 - karger.com
Background: If loss of functioning nephrons predisposes to glomerular barotrauma (a
“remnant nephron” effect), then glomerular permeability should increase as glomerular …

Acquired C1-inhibitor deficiency presenting with nephrotic syndrome

J Willows, K Wood, H Bourne… - BMJ Case Reports …, 2019 - casereports.bmj.com
Acquired C1-inhibitor (C1-INH) deficiency is a rare and potentially life-threatening disorder,
which presents with recurrent attacks of non-pitting oedema to the face, airway, limbs or …

[HTML][HTML] Remove the “Strict” From “Restriction”: A# NephJC Editorial on SODIUM-HF

SB Khalid, R Hung, WAV Espinosa… - Kidney …, 2023 - kidneymedicinejournal.org
Background Dietary sodium restriction is commonly recommended to ambulatory patients
with heart failure by clinicians worldwide, in the hope of preventing volume overload and …

[HTML][HTML] Acetaminophen Exacerbates Hypertension: A# NephJC Editorial on PATH-BP

P John, C Popa, M Abbasi, J Teakell… - Kidney …, 2022 - kidneymedicinejournal.org
Pain is very common, and therefore so is the use of analgesics. If analgesics in widespread
use even slightly increase cardiovascular risk, the knock-on effects can be huge; if the single …