[HTML][HTML] The role of complement in kidney disease
J Willows, M Brown, NS Sheerin - Clinical Medicine, 2020 - ncbi.nlm.nih.gov
While the complement cascade is an important component of the innate immune system,
uncontrolled activation can cause severe disease. This concept is illustrated by the …
uncontrolled activation can cause severe disease. This concept is illustrated by the …
The challenges of diagnosis and management of Gitelman syndrome
S Urwin, J Willows, JA Sayer - Clinical Endocrinology, 2020 - Wiley Online Library
Gitelman syndrome is an inherited tubulopathy characterized by renal salt wasting from the
distal convoluted tubule. Defects in the sodium chloride cotransporter (encoded by …
distal convoluted tubule. Defects in the sodium chloride cotransporter (encoded by …
Acute interstitial nephritis due to sodium-glucose co-transporter 2 inhibitor empagliflozin
Biopsy-proven acute interstitial nephritis (AIN) secondary to sodium-glucose co-transporter 2
(SGLT2) inhibitors has not been described previously. Here, we report on the management …
(SGLT2) inhibitors has not been described previously. Here, we report on the management …
[HTML][HTML] Case report: investigation and molecular genetic diagnosis of familial hypomagnesaemia
J Willows, M Al Badi, C Richardson, A Al Sinani… - …, 2019 - ncbi.nlm.nih.gov
Genetic mutations causing familial hypomagnesaemia syndromes are well-recognised.
Affected patients can present with severe symptoms of hypomagnesaemia, such as seizures …
Affected patients can present with severe symptoms of hypomagnesaemia, such as seizures …
Seasonal hypercalcaemia; consider CYP24A1 mutation
J Willows, JA Sayer - QJM: An International Journal of Medicine, 2019 - academic.oup.com
Dear Editor, We read with interest the case report entitled 'Seasonal Hypercalcaemia'. 1 We
wish to congratulate the authors on reporting this interesting case, and hoped to make some …
wish to congratulate the authors on reporting this interesting case, and hoped to make some …
Use of Terlipressin in AKI Associated Hepatorenal Syndrome: CON
J Willows, S Hiremath - Kidney360, 2024 - journals.lww.com
Disclosures: ASN journals have adopted the ASN Conflict of Interest and Disclosure Policy,
available here. In summary, authors should disclose any financial relationships or …
available here. In summary, authors should disclose any financial relationships or …
changing protein permeability with nephron loss: Evidence for a human remnant nephron effect
Background: If loss of functioning nephrons predisposes to glomerular barotrauma (a
“remnant nephron” effect), then glomerular permeability should increase as glomerular …
“remnant nephron” effect), then glomerular permeability should increase as glomerular …
Acquired C1-inhibitor deficiency presenting with nephrotic syndrome
J Willows, K Wood, H Bourne… - BMJ Case Reports …, 2019 - casereports.bmj.com
Acquired C1-inhibitor (C1-INH) deficiency is a rare and potentially life-threatening disorder,
which presents with recurrent attacks of non-pitting oedema to the face, airway, limbs or …
which presents with recurrent attacks of non-pitting oedema to the face, airway, limbs or …
[HTML][HTML] Remove the “Strict” From “Restriction”: A# NephJC Editorial on SODIUM-HF
SB Khalid, R Hung, WAV Espinosa… - Kidney …, 2023 - kidneymedicinejournal.org
Background Dietary sodium restriction is commonly recommended to ambulatory patients
with heart failure by clinicians worldwide, in the hope of preventing volume overload and …
with heart failure by clinicians worldwide, in the hope of preventing volume overload and …
[HTML][HTML] Acetaminophen Exacerbates Hypertension: A# NephJC Editorial on PATH-BP
Pain is very common, and therefore so is the use of analgesics. If analgesics in widespread
use even slightly increase cardiovascular risk, the knock-on effects can be huge; if the single …
use even slightly increase cardiovascular risk, the knock-on effects can be huge; if the single …