Evaluation of drug-drug interaction in the hepatobiliary and renal transport of drugs

Y Shitara, H Sato, Y Sugiyama - Annu. Rev. Pharmacol. Toxicol., 2005 - annualreviews.org
▪ Abstract Recent studies have revealed the import role played by transporters in the renal
and hepatobiliary excretion of many drugs. These transporters exhibit a broad substrate …

Selectivity coefficients for ion-selective electrodes: Recommended methods for reporting KA, Bpot values (Technical Report)

Y Umezawa, K Umezawa, H Sato - Pure and applied chemistry, 1995 - degruyter.com
SELECTIVITY COEFFICIENTS FOR METHODS FOR REPORTING Krb VALUES ION-SELECTIVE
ELECTRODES: RECOMMENDED Page 1 Pure & Appl. Chern., Vol. No. 3, pp. 507-518, 1995 …

Effects of exercise therapy on painful temporomandibular disorders

A Shimada, S Ishigaki, Y Matsuka… - Journal of oral …, 2019 - Wiley Online Library
Temporomandibular disorders (TMD) are common chronic musculoskeletal pain conditions
among orofacial pain. Painful TMD condition such as myalgia and arthralgia can be …

Emerging issues in radiogenic cataracts and cardiovascular disease

N Hamada, Y Fujimichi, T Iwasaki, N Fujii… - Journal of radiation …, 2014 - academic.oup.com
Abstract In 2011, the International Commission on Radiological Protection issued a
statement on tissue reactions (formerly termed non-stochastic or deterministic effects) to …

Early statin treatment in patients with acute coronary syndrome: demonstration of the beneficial effect on atherosclerotic lesions by serial volumetric intravascular …

S Okazaki, T Yokoyama, K Miyauchi, K Shimada… - Circulation, 2004 - Am Heart Assoc
Background—Recent clinical trials have demonstrated that aggressive lipid lowering by
statins could prevent recurrent events after acute coronary syndrome (ACS). We …

Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1: SLC21A6)-mediated hepatic uptake and CYP2C8-mediated …

Y Shitara, M Hirano, H Sato, Y Sugiyama - Journal of Pharmacology and …, 2004 - ASPET
A serious pharmacokinetic interaction between cerivastatin (CER) and gemfibrozil (GEM)
has been reported. In the present study, we examined the inhibitory effects of GEM and its …

Inhibition of transporter-mediated hepatic uptake as a mechanism for drug-drug interaction between cerivastatin and cyclosporin A

Y Shitara, T Itoh, H Sato, AP Li, Y Sugiyama - Journal of Pharmacology and …, 2003 - ASPET
The mechanism involved in the clinically relevant drug-drug interaction (DDI) between
cerivastatin (CER) and cyclosporin A (CsA) has not yet been clarified. In the present study …

Hypocholesterolemic and antioxidant effects of aqueous extracts from the dried calyx of Hibiscus sabdariffa L. in hypercholesterolemic rats

V Hirunpanich, A Utaipat, NP Morales… - Journal of …, 2006 - Elsevier
The present study was designed to investigate the hypolipidemic effects and antioxidant
effects of Hibiscus sabdariffa L.(roselle) with regard to protection of LDL oxidation in vivo …

[HTML][HTML] Effects of novel capsinoid treatment on fatness and energy metabolism in humans: possible pharmacogenetic implications

S Snitker, Y Fujishima, H Shen, S Ott… - The American journal of …, 2009 - Elsevier
Abstract Background Capsinoids from the Capsicum genus of plants are nonpungent
capsaicin-related substances with effects on metabolism and body weight in animals …

Therapeutic basis of glycyrrhizin on chronic hepatitis B

H Sato, W Goto, J Yamamura, M Kurokawa… - Antiviral research, 1996 - Elsevier
Glycyrrhizin, a major component of a herb (licorice), has been intravenously used for the
treatment of chronic hepatitis B in Japan and improves liver function with occasional …