Abstract COVID-19, caused by SARS-CoV-2, continues to be a major health problem since
its first description in Wuhan, China, in December 2019. Multiple drugs have been tried to …

Background Whether pembrolizumab given both before surgery (neoadjuvant therapy) and
after surgery (adjuvant therapy), as compared with pembrolizumab given as adjuvant …

Soft tissue sarcoma (STS) is a biologically heterogeneous malignancy with over 50
subtypes. Historically, there have been few systemic treatment options for this relatively rare …

Autophagy maintains homeostasis and is induced upon stress. Yet, its mechanistic
interaction with oncogenic signaling remains elusive. Here, we show that in BRAFV600E …

BRAF mutations are relatively common in many cancers, particularly melanoma, colorectal
cancer, and thyroid cancer and to a lesser extent in lung cancer. These mutations can be …

Purpose Approximately 5% of patients with cutaneous squamous cell carcinoma (CSCC)
may develop recurrent or metastatic disease. The management of such cases is challenging …

Background: Brain metastases are a significant cause of mortality and morbidity for patients
with melanoma. We hypothesize that the development of brain metastases may be …

The introduction of nanotechnology has brought about major progress in modern medicine.
Nanotechnology involves the use of nanosized materials, or those measured at the level of 1 …

Melanoma brain metastases (MBM) are clinically challenging to treat and exhibit variable
responses to immune checkpoint therapies. Prior research suggests that MBM exhibit poor …

Background There is limited literature regarding potential disparities in nonmelanoma skin
cancer for patients with skin of color. Objective Use the sizes of Mohs micrographic surgery …