[HTML][HTML] Diabetic cardiomyopathy: Pathophysiology, diagnostic evaluation and management

JM Pappachan, GI Varughese, R Sriraman… - World journal of …, 2013 - ncbi.nlm.nih.gov
Diabetes affects every organ in the body and cardiovascular disease accounts for two-thirds
of the mortality in the diabetic population. Diabetes-related heart disease occurs in the form …

Is hypertension a prothrombotic state?

GI Varughese, GYH Lip - Current hypertension reports, 2005 - Springer
Hypertension is complicated by thrombosis-related events (such as myocardial infarction
and stroke), and despite the high vascular pressures, these thrombotic occlusive events …

Angiopoietin‐2 levels as a biomarker of cardiovascular risk in patients with hypertension

JV Patel, HS Lim, GI Varughese, EA Hughes… - Annals of …, 2008 - Taylor & Francis
Background. Abnormal angiogenesis is a pathophysiological component of cardiovascular
disease (CVD), where circulating biomarkers of angiogenesis are associated with increased …

Diabetes mellitus and atrial fibrillation: perspectives on epidemiological and pathophysiological links

GYH Lip, GI Varughese - International journal of cardiology, 2005 - Elsevier
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, which is also
associated with a substantial risk of mortality and morbidity from stroke, thromboembolism …

Bariatric surgery and diabetic retinopathy: a pilot analysis

L Varadhan, T Humphreys, AB Walker, CVN Cheruvu… - Obesity surgery, 2012 - Springer
To the Editor, Rapid and significant improvement in diabetes control is known to worsen
diabetic retinopathy (DR). This clinical paradox has been well noted during intensification of …

GLP-1 agonist treatment: implications for diabetic retinopathy screening

L Varadhan, T Humphreys, C Hariman… - Diabetes Research and …, 2011 - Elsevier
Rapid improvement in glycaemic control induced by GLP-1 agonist therapy could be yet
another illustration of transient or permanent progression of diabetic retinopathy, similar to …

The impact of improved glycaemic control with GLP-1 receptor agonist therapy on diabetic retinopathy

L Varadhan, T Humphreys, AB Walker… - Diabetes Research and …, 2014 - Elsevier
Rapid improvement in glycaemic control with GLP-1 receptor agonist (RA) therapy has been
reported to be associated with significant progression of diabetic retinopathy. This …

[HTML][HTML] Challenges of emerging adulthood-transition from paediatric to adult diabetes

G Gill, AU Nayak, J Wilkins, J Hankey… - World journal of …, 2014 - ncbi.nlm.nih.gov
Diabetes mellitus is a complex condition with far reaching physical, psychological and
psychosocial effects. These outcomes can be significant when considering the care of a …

Targeting the renin-angiotensin-aldosterone-system in atrial fibrillation: a shift from electrical to structural therapy?

A Choudhury, GI Varughese… - Expert Opinion on …, 2005 - Taylor & Francis
Despite its increasing incidence and prevalence, treatment options in atrial fibrillation (AF)
are far from ideal and often limited. After decades of focus on the electrical aspects of AF …

Effects of blood pressure on the prothrombotic risk in 1235 patients with non-valvular atrial fibrillation

GI Varughese, JV Patel, J Tomson, GYH Lip - Heart, 2007 - heart.bmj.com
Background: Increased levels of plasma von Willebrand factor (vWf, an index of endothelial
damage/dysfunction) and soluble P-selectin (sP-sel, an index of platelet activation) …