User profiles for "author:Fabrizio Mancini"

Fabrizio Edoardo Mancini

Manchester Metropolitan University
Verified email at mmu.ac.uk
Cited by 30

[HTML][HTML] Developmental principles informing human pluripotent stem cell differentiation to cartilage and bone

PA Humphreys, FE Mancini, MJS Ferreira… - Seminars in cell & …, 2022 - Elsevier
Human pluripotent stem cells can differentiate into any cell type given appropriate signals
and hence have been used to research early human development of many tissues and …

Pluripotent stem cells for skeletal tissue engineering

MJS Ferreira, FE Mancini, PA Humphreys… - Critical Reviews in …, 2022 - Taylor & Francis
Here, we review the use of human pluripotent stem cells for skeletal tissue engineering. A
number of approaches have been used for generating cartilage and bone from both human …

[HTML][HTML] Inhibition of angiogenesis mediated by extremely low-frequency magnetic fields (ELF-MFs)

S Delle Monache, A Angelucci, P Sanitą, R Iorio… - PLoS …, 2013 - journals.plos.org
The formation of new blood vessels is an essential therapeutic target in many diseases such
as cancer, ischemic diseases, and chronic inflammation. In this regard, extremely low …

[PDF][PDF] Optogenetic manipulation of BMP signaling to drive chondrogenic differentiation of hPSCs

PEA Humphreys, S Woods, N Bates, KM Rooney… - Cell Reports, 2023 - cell.com
Optogenetics is a rapidly advancing technology combining photochemical, optical, and
synthetic biology to control cellular behavior. Together, sensitive light-responsive …

Planum temporale asymmetry and thought disorder in schizophrenia

A Rossi, A Serio, P Stratta, C Petruzzi, G Schiazza… - Schizophrenia …, 1994 - Elsevier
Magnetic resonance imaging (MRI) was used to investigate the size and the asymmetry of
the planum temporale (PT) in 22 schizophrenic patients and 23 strictly matched healthy …

[HTML][HTML] Precision nutrition to reset virus-induced human metabolic reprogramming and dysregulation (HMRD) in long-COVID

AS Naidu, CK Wang, P Rao, F Mancini… - npj Science of …, 2024 - nature.com
Abstract SARS‐CoV‐2, the etiological agent of COVID-19, is devoid of any metabolic
capacity; therefore, it is critical for the viral pathogen to hijack host cellular metabolic …

Magnetic resonance imaging findings of amygdala-anterior hippocampus shrinkage in male patients with schizophrenia

A Rossi, P Stratta, F Mancini, M Gallucci, P Mattei… - Psychiatry …, 1994 - Elsevier
Recent magnetic resonance imaging (MRI) studies found abnormalities of medial temporal
lobe and basal ganglia structures. We used an inversion recovery (IR) protocol with the …

[HTML][HTML] Effect of a retinoic acid analogue on BMP-driven pluripotent stem cell chondrogenesis

FE Mancini, PEA Humphreys, S Woods, N Bates… - Scientific Reports, 2024 - nature.com
Osteoarthritis is the most common degenerative joint condition, leading to articular cartilage
(AC) degradation, chronic pain and immobility. The lack of appropriate therapies that …

[HTML][HTML] Directed differentiation of hPSCs through a simplified lateral plate mesoderm protocol for generation of articular cartilage progenitors

CA Smith, PA Humphreys, MA Naven, S Woods… - Plos one, 2023 - journals.plos.org
Developmentally, the articular joints are derived from lateral plate (LP) mesoderm. However,
no study has produced both LP derived prechondrocytes and preosteoblasts from human …

A new protocol for regio-and stereocontrolled aldol reactions through the conjugate addition of dialkylboranes to. alpha.,. beta.-unsaturated ketones

GP Boldrini, M Bortolotti, F Mancini… - The Journal of …, 1991 - ACS Publications
A one-pot, two-step procedure, consisting of the 1, 4-addition of dialkylboranes to ß-
substituted (E)-a,/S-unsaturated ketones followed by the reaction of the resulting …