Role of the Pseudomonas aeruginosa oxyR-recG operon in oxidative stress defense and DNA repair: OxyR-dependent regulation of katB-ankB, ahpB, and ahpC-ahpF

UA Ochsner, ML Vasil, E Alsabbagh… - Journal of …, 2000 - Am Soc Microbiol
Pseudomonas aeruginosa possesses an extensive armament of genes involved in oxidative
stress defense, including katB-ankB, ahpB, and ahpC-ahpF. Transcription of these genes …

Isoprene in the exhaled breath is a novel biomarker for advanced fibrosis in patients with chronic liver disease: a pilot study

N Alkhouri, T Singh, E Alsabbagh… - Clinical and …, 2015 - journals.lww.com
OBJECTIVES: Analysis of volatile organic compounds (VOCs) in the exhaled breath can
identify markers for alcoholic and nonalcoholic fatty liver disease. The aim of this pilot study …

A Protease-Resistant Catalase, KatA, Released upon Cell Lysis during Stationary Phase Is Essential for Aerobic Survival of a Pseudomonas aeruginosa oxyR Mutant …

DJ Hassett, E Alsabbagh, K Parvatiyar… - Journal of …, 2000 - Am Soc Microbiol
ABSTRACT A Pseudomonas aeruginosa oxyR mutant was dramatically sensitive to H2O2,
despite possessing wild-type catalase activity. Oxygen-dependent oxyR phenotypes also …

Global Analysis of Cellular Factors and Responses Involved in Pseudomonas aeruginosa Resistance to Arsenite

K Parvatiyar, EM Alsabbagh, UA Ochsner… - Journal of …, 2005 - Am Soc Microbiol
The impact of arsenite [As (III)] on several levels of cellular metabolism and gene regulation
was examined in Pseudomonas aeruginosa. P. aeruginosa isogenic mutants devoid of …

AnkB, a Periplasmic Ankyrin-Like Protein inPseudomonas aeruginosa, Is Required for Optimal Catalase B (KatB) Activity and Resistance to Hydrogen Peroxide

ML Howell, E Alsabbagh, JF Ma… - Journal of …, 2000 - Am Soc Microbiol
In this study, we have cloned the ankB gene, encoding an ankyrin-like protein in
Pseudomonas aeruginosa. The ankB gene is composed of 549 bp encoding a protein of …

Outcomes of kidney, liver, and simultaneous liver and kidney transplants from hepatitis c infected donors to hepatitis c naïve recipients: A large single center …

H Elbeshbeshy, N Modi, T Patel… - Clinical …, 2024 - Wiley Online Library
Background With the introduction of direct‐acting antiviral therapies (DAAs), the non‐use
rate of hepatitis C virus (HCV)‐positive donor organs (D+) has decreased significantly. We …

Glecaprevir/pibrentasvir-associated acute liver injury in non-cirrhotic, chronic HCV infection without HBV co-infection

MB Hammami, R Aboushaar… - BMJ Case Reports …, 2019 - casereports.bmj.com
The combination of glecaprevir and pibrentasvir was recently approved for chronic hepatitis
C virus (HCV) infection with recommended treatment duration of 8–12 weeks depending on …

S3442 A 70-Year-Old Patient With Elevated Liver Enzymes for Many Years and No Fibrosis: An Unusual Diagnosis

P Yarra, DY Alsabbagh, EZ Gharaibeh… - Official journal of the …, 2023 - journals.lww.com
Discussion: TS is a rare disease with a median age of diagnosis of 15 years and a reported
prevalence of elevated liver enzymes in 20%-80% of the cases. Many patients with TS who …

S2570 Elevated Manganese Levels: A Case Report of an Unusual Presentation in a Patient With Cirrhosis and Iron-Deficiency Anemia

S Ravichandran, E Alsabbagh… - Official journal of the …, 2020 - journals.lww.com
DISCUSSION: Pallidal signal hyperintensity on T1-weighted MRI has been well described in
patients with Parkinson's disease and in patients with Mn toxicity. Increased Mn levels have …

[HTML][HTML] Case Report: Glecaprevir/pibrentasvir-associated acute liver injury in non-cirrhotic, chronic HCV infection without HBV co-infection

MB Hammami, R Aboushaar, E Alsabbagh - BMJ Case Reports, 2019 - ncbi.nlm.nih.gov
The combination of glecaprevir and pibrentasvir was recently approved for chronic hepatitis
C virus (HCV) infection with recommended treatment duration of 8–12 weeks depending on …