[HTML][HTML] Effects of hyperglycemia and diabetes mellitus on coagulation and hemostasis
X Li, NC Weber, DM Cohn, MW Hollmann… - Journal of clinical …, 2021 - mdpi.com
In patients with diabetes, metabolic disorders disturb the physiological balance of
coagulation and fibrinolysis, leading to a prothrombotic state characterized by platelet …
coagulation and fibrinolysis, leading to a prothrombotic state characterized by platelet …
[HTML][HTML] The international WAO/EAACI guideline for the management of hereditary angioedema–The 2021 revision and update
Hereditary Angioedema (HAE) is a rare and disabling disease for which early diagnosis and
effective therapy are critical. This revision and update of the global WAO/EAACI guideline on …
effective therapy are critical. This revision and update of the global WAO/EAACI guideline on …
Thrombophilia testing for prevention of recurrent venous thromboembolism
DM Cohn, F Vansenne, CA de Borgie… - … of systematic reviews, 2012 - cochranelibrary.com
Background Tests for thrombophilia are being performed on a large scale in people after
venous thromboembolism (VTE) even though the benefits of testing are still subject to …
venous thromboembolism (VTE) even though the benefits of testing are still subject to …
Thrombophilia and venous thromboembolism: implications for testing
DM Cohn, S Roshani… - Seminars in thrombosis …, 2007 - thieme-connect.com
In the last decades, the knowledge on the etiology of venous thromboembolism (VTE) has
increased tremendously. In approximately half of patients presenting with VTE, one or more …
increased tremendously. In approximately half of patients presenting with VTE, one or more …
[HTML][HTML] Inhibition of prekallikrein for hereditary angioedema
LM Fijen, MA Riedl, L Bordone… - … England Journal of …, 2022 - Mass Medical Soc
Background Hereditary angioedema is characterized by recurrent and unpredictable
swellings that are disabling and potentially fatal. Selective inhibition of plasma prekallikrein …
swellings that are disabling and potentially fatal. Selective inhibition of plasma prekallikrein …
Quality of life after pulmonary embolism as assessed with SF-36 and PEmb-QoL
J van Es, PL den Exter, AA Kaptein, CD Andela… - Thrombosis research, 2013 - Elsevier
Introduction Although quality of life (QoL) is recognized as an important indicator of the
course of a disease, it has rarely been addressed in studies evaluating the outcome of care …
course of a disease, it has rarely been addressed in studies evaluating the outcome of care …
An investigational oral plasma kallikrein inhibitor for on-demand treatment of hereditary angioedema: a two-part, randomised, double-blind, placebo-controlled …
E Aygören-Pürsün, A Zanichelli, DM Cohn, M Cancian… - The Lancet, 2023 - thelancet.com
Background Guidelines recommend effective on-demand therapy for all individuals with
hereditary angioedema. We aimed to assess the novel oral plasma kallikrein inhibitor …
hereditary angioedema. We aimed to assess the novel oral plasma kallikrein inhibitor …
[HTML][HTML] Current and prospective targets of pharmacologic treatment of hereditary angioedema types 1 and 2
LM Fijen, K Bork, DM Cohn - Clinical reviews in allergy & immunology, 2021 - Springer
Hereditary angioedema (HAE) is a rare disease that causes episodic attacks of
subcutaneous and submucosal edema, which can be painful, incapacitating, and potentially …
subcutaneous and submucosal edema, which can be painful, incapacitating, and potentially …
Definition, aims, and implementation of GA2LEN/HAEi Angioedema Centers of Reference and Excellence
To the Editor, GA2LEN, the Global Allergy and Asthma European Network, and HAE
international (HAEi), the global umbrella organization for the world's hereditary angioedema …
international (HAEi), the global umbrella organization for the world's hereditary angioedema …
[HTML][HTML] Antisense inhibition of prekallikrein to control hereditary angioedema
DM Cohn, NJ Viney, LM Fijen… - … England Journal of …, 2020 - Mass Medical Soc
Hereditary angioedema is characterized by recurrent and unpredictable episodes of
subcutaneous and mucosal swelling that can be life threatening. IONIS-PKK-LRx is a ligand …
subcutaneous and mucosal swelling that can be life threatening. IONIS-PKK-LRx is a ligand …