Role of oxidants and antioxidants in atherosclerosis: results of in vitro and in vivo investigations
R Siekmeier, C Steffen, W März - Journal of cardiovascular …, 2007 - journals.sagepub.com
Both in vitro and in vivo studies have shown that oxidants are central in the development of
atherosclerosis. Consequently, additional studies evaluated the protective effects of various …
atherosclerosis. Consequently, additional studies evaluated the protective effects of various …
[HTML][HTML] NMR evaluation of total statin content and HMG-CoA reductase inhibition in red yeast rice (Monascus spp.) food supplements
DW Lachenmeier, YB Monakhova, T Kuballa… - Chinese medicine, 2012 - Springer
Background Red yeast rice (ie., rice fermented with Monascus spp.), as a food supplement,
is claimed to be blood cholesterol-lowering. The red yeast rice constituent monacolin K, also …
is claimed to be blood cholesterol-lowering. The red yeast rice constituent monacolin K, also …
What is a food and what is a medicinal product in the European Union? Use of the benchmark dose (BMD) methodology to define a threshold for “pharmacological …
DW Lachenmeier, C Steffen, O el-Atma… - Regulatory Toxicology …, 2012 - Elsevier
The decision criterion for the demarcation between foods and medicinal products in the EU
is the significant “pharmacological action”. Based on six examples of substances with …
is the significant “pharmacological action”. Based on six examples of substances with …
Severe chlorate poisoning: report of a case
C Steffen, R Seitz - Archives of toxicology, 1981 - Springer
A case of severe sodium chlorate poisoning was observed within 5 h after suicidal ingestion
of 150–200 g of the herbicide. Methaemoglobinaemia was the early symptom of the …
of 150–200 g of the herbicide. Methaemoglobinaemia was the early symptom of the …
On the mechanism of paraquat action on microsomal oxygen reduction and its relation to lipid peroxidation
C Steffen, KJ Netter - Toxicology and Applied Pharmacology, 1979 - Elsevier
Liver microsomes from control and phenobarbital-induced (PB) mice have been used to
study the effect of paraquat (PQ) on oxygen reduction and malondialdehyde (MDA) …
study the effect of paraquat (PQ) on oxygen reduction and malondialdehyde (MDA) …
[HTML][HTML] The influence of chronic l-carnitine supplementation on the formation of preneoplastic and atherosclerotic lesions in the colon and aorta of male F344 rats
MT Empl, P Kammeyer, R Ulrich, JF Joseph… - Archives of …, 2015 - Springer
Abstract l-Carnitine, a key component of fatty acid oxidation, is nowadays being extensively
used as a nutritional supplement with allegedly “fat burning” and performance-enhancing …
used as a nutritional supplement with allegedly “fat burning” and performance-enhancing …
Lack of in vivo lipid peroxidation in experimental paraquat poisoning
C Steffen, H Muliawan, H Kappus - Naunyn-Schmiedeberg's Archives of …, 1980 - Springer
Ethane evolution was measured in rats breathing pure oxygen. Animals injected ip with a
lethal dose of paraquat (50 mg/kg) developed signs of pulmonary insufficiency within 3 …
lethal dose of paraquat (50 mg/kg) developed signs of pulmonary insufficiency within 3 …
Red yeast rice: An unsafe food supplement?
C Steffen - Bundesgesundheitsblatt, Gesundheitsforschung …, 2017 - europepmc.org
Red yeast rice is the fermentation product of the mould Monascus ruber and is traditionally
used in East Asia to dye and conserve food. Its main pharmacologically active compound …
used in East Asia to dye and conserve food. Its main pharmacologically active compound …
The dilemma of approving antidotes
C Steffen - Toxicology, 2007 - Elsevier
Clinical trials with antidotes are difficult to perform for a variety of practical, ethical, and
financial reasons. As acute poisoning is a rare event, the commercial interest in basic and …
financial reasons. As acute poisoning is a rare event, the commercial interest in basic and …
Short-term effect of whole milk and milk fermented by Pseudomonas fluorescens on plasma lipids in adult boars
P Stoll, A Gutzwiller, M Jost, H Schneeberger… - British journal of …, 1991 - cambridge.org
The short-term effects of whole milk and milk fermented by Pseudomonas fluorescens, of the
amino acid composition of the diet and of feeding frequency on the level of plasma lipids …
amino acid composition of the diet and of feeding frequency on the level of plasma lipids …