Scedosporium and Lomentospora: an updated overview of underrated opportunists

A Ramirez-Garcia, A Pellon, A Rementeria… - Medical …, 2018 - academic.oup.com
Abstract Species of Scedosporium and Lomentospora are considered as emerging
opportunists, affecting immunosuppressed and otherwise debilitated patients, although …

Antibiotic resistance is ancient

VM D'Costa, CE King, L Kalan, M Morar, WWL Sung… - Nature, 2011 - nature.com
The discovery of antibiotics more than 70 years ago initiated a period of drug innovation and
implementation in human and animal health and agriculture. These discoveries were …

Metagenomics to paleogenomics: large-scale sequencing of mammoth DNA

HN Poinar, C Schwarz, J Qi, B Shapiro, RDE MacPhee… - science, 2006 - science.org
We sequenced 28 million base pairs of DNA in a metagenomics approach, using a woolly
mammoth (Mammuthus primigenius) sample from Siberia. As a result of exceptional sample …

[HTML][HTML] Progress in definition, prevention and treatment of fungal infections in cystic fibrosis

C Schwarz, D Hartl, O Eickmeier, A Hector, C Benden… - Mycopathologia, 2018 - Springer
Cystic fibrosis (CF) is a chronic lethal multi-system condition; however, most of the morbidity
and mortality is dependent on the status of the respiratory system. Progressive respiratory …

[PDF][PDF] Genomewide comparison of DNA sequences between humans and chimpanzees

I Ebersberger, D Metzler, C Schwarz… - The American Journal of …, 2002 - cell.com
A total of 8,859 DNA sequences encompassing∼ 1.9 million base pairs of the chimpanzee
genome were sequenced and compared to corresponding human DNA sequences …

[PDF][PDF] Human anti-fungal Th17 immunity and pathology rely on cross-reactivity against Candida albicans

P Bacher, T Hohnstein, E Beerbaum, M Röcker… - Cell, 2019 - cell.com
Th17 cells provide protection at barrier tissues but may also contribute to immune pathology.
The relevance and induction mechanisms of pathologic Th17 responses in humans are …

[PDF][PDF] Regulatory T cell specificity directs tolerance versus allergy against aeroantigens in humans

P Bacher, F Heinrich, U Stervbo, M Nienen… - Cell, 2016 - cell.com
FOXP3+ regulatory T cells (Tregs) maintain tolerance against self-antigens and innocuous
environmental antigens. However, it is still unknown whether Treg-mediated tolerance is …

New insights from old bones: DNA preservation and degradation in permafrost preserved mammoth remains

C Schwarz, R Debruyne, M Kuch… - Nucleic acids …, 2009 - academic.oup.com
Despite being plagued by heavily degraded DNA in palaeontological remains, most studies
addressing the state of DNA degradation have been limited to types of damage which do not …

[HTML][HTML] CFTR modulator therapy and its impact on lung transplantation in cystic fibrosis

C Benden, C Schwarz - Pulmonary Therapy, 2021 - Springer
Cystic fibrosis (CF) is the most common autosomal recessive disorder in Caucasian people
and is caused by mutations in the gene encoding for the CF transmembrane conductance …

Single nucleotide polymorphism (SNP) discovery in mammals: a targeted‐gene approach

N Aitken, S Smith, C Schwarz, PA Morin - Molecular ecology, 2004 - Wiley Online Library
Single nucleotide polymorphisms (SNPs) have rarely been exploited in nonhuman and
nonmodel organism genetic studies. This is due partly to difficulties in finding SNPs in …