User profiles for "author:Buddha Basnyat"

Buddha Basnyat

Director, Oxford University Clinical Research Unit\Nepal
Verified email at wlink.com.np
Cited by 22262

High-altitude illness

B Basnyat, DR Murdoch - The Lancet, 2003 - thelancet.com
High-altitude illness is the collective term for acute mountain sickness (AMS), high-altitude
cerebral oedema (HACE), and high-altitude pulmonary oedema (HAPE). The …

Maximising access to achieve appropriate human antimicrobial use in low-income and middle-income countries

M Mendelson, JA Røttingen, U Gopinathan, DH Hamer… - The Lancet, 2016 - thelancet.com
Access to quality-assured antimicrobials is regarded as part of the human right to health, yet
universal access is often undermined in low-income and middle-income countries. Lack of …

Clinical recommendations for high altitude exposure of individuals with pre-existing cardiovascular conditions

G Parati, P Agostoni, B Basnyat, G Bilo… - European heart …, 2018 - academic.oup.com
Take home figure Adapted from Bärtsch and Gibbs Physiological response to hypoxia. Life-
sustaining oxygen delivery, in spite of a reduction in the partial pressure of inhaled oxygen …

[HTML][HTML] Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis

CJL Murray, KS Ikuta, F Sharara, L Swetschinski… - The lancet, 2022 - thelancet.com
Background Antimicrobial resistance (AMR) poses a major threat to human health around
the world. Previous publications have estimated the effect of AMR on incidence, deaths …

[HTML][HTML] Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events

VK Wong, S Baker, DJ Pickard, J Parkhill, AJ Page… - Nature …, 2015 - nature.com
The emergence of multidrug-resistant (MDR) typhoid is a major global health threat affecting
many countries where the disease is endemic. Here whole-genome sequence analysis of …

Antimicrobial Drug Resistance of Salmonella enterica Serovar Typhi in Asia and Molecular Mechanism of Reduced Susceptibility to the Fluoroquinolones

TT Chau, JI Campbell, CM Galindo… - Antimicrobial agents …, 2007 - Am Soc Microbiol
This study describes the pattern and extent of drug resistance in 1,774 strains of Salmonella
enterica serovar Typhi isolated across Asia between 1993 and 2005 and characterizes the …

Salmonella enterica Serovar Paratyphi A and S. enterica Serovar Typhi Cause Indistinguishable Clinical Syndromes in Kathmandu, Nepal

AP Maskey, JN Day, PQ Tuan… - Clinical infectious …, 2006 - academic.oup.com
Background. Enteric fever is a major global problem. Emergence of antibacterial resistance
threatens to render current treatments ineffective. There is little research or public health …

[PDF][PDF] The etiology of febrile illness in adults presenting to Patan hospital in Kathmandu, Nepal

DR Murdoch, CW Woods, MD Zimmerman… - American Journal of …, 2004 - researchgate.net
In Nepal, many infections remain poorly characterized, partly due to limited diagnostic
facilities. We studied consecutive febrile adults presenting to a general hospital in …

[HTML][HTML] Admixture facilitates genetic adaptations to high altitude in Tibet

C Jeong, G Alkorta-Aranburu, B Basnyat… - Nature …, 2014 - nature.com
Admixture is recognized as a widespread feature of human populations, renewing interest in
the possibility that genetic exchange can facilitate adaptations to new environments. Studies …

Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma

CC Khor, T Do, H Jia, M Nakano, R George… - Nature …, 2016 - nature.com
Primary angle closure glaucoma (PACG) is a major cause of blindness worldwide. We
conducted a genome-wide association study (GWAS) followed by replication in a combined …