The factors driving therapy resistance in diffuse glioma remain poorly understood. To identify
treatment-associated cellular and genetic changes, we analyzed RNA and/or DNA …

The evolutionary processes that drive universal therapeutic resistance in adult patients with
diffuse glioma remain unclear,. Here we analysed temporally separated DNA-sequencing …

Background Amyloid positron emission tomography (PET) has become an important tool to
identify amyloid-β (Aβ) pathology in Alzheimer's disease (AD) patients. Here, we determined …

In vivo imaging of fibrillar β-amyloid deposits may assist clinical diagnosis of Alzheimer's
disease (AD), aid treatment selection for patients, assist clinical trials of therapeutic drugs …

Background Marked variation exists in the use of genomic data in tumour diagnosis, and
optimal integration with conventional diagnostic technology remains uncertain despite …

Introduction Facial trauma is a frequent presentation to the emergency department following
alcohol related injuries. Brief alcohol intervention (BAI) is a form of a motivational interview …

Despite significant impacts of natural ventilation on atria, indoor thermal conditions and
decreasing energy usage load, there is lack of knowledge about how various design …

Atypical teratoid rhabdoid tumour (ATRT) is a rare and highly aggressive malignant
neoplasm of the central nervous system (CNS), which occurs predominantly in children less …

The deposition of the amyloid β-protein (Aβ) in senile plaques is one of the histopathological
hallmarks of Alzheimer's disease (AD). Aβ-plaques arise first in neocortical areas and, then …

Revised: 21 May 2017/Accepted: 21 May 2017/Published online: 25 May 2017© Springer-
Verlag Berlin Heidelberg 2017 arms 1p and 19q were examined by interphase fluorescence …