Cerebrospinal fluid TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis patients with and without the C9ORF72 hexanucleotide expansion
A Junttila, M Kuvaja, P Hartikainen, M Siloaho… - Dementia and geriatric …, 2016 - karger.com
Background: TDP-43 is the main protein component of ubiquitinated inclusions in a
subgroup of frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis …
subgroup of frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis …
Tertiary lymphoid structures and gastric cancer prognosis
N Kemi, O Ylitalo, JP Väyrynen, O Helminen, A Junttila… - Apmis, 2023 - Wiley Online Library
Tertiary lymphoid structures (TLSs) are part of immune response against cancer. Their high
density and high diameter have been shown to be associated with prognosis in different …
density and high diameter have been shown to be associated with prognosis in different …
[HTML][HTML] Immunophenotype based on inflammatory cells, PD-1/PD-L1 signalling pathway and M2 macrophages predicts survival in gastric cancer
A Junttila, O Helminen, JP Väyrynen… - British Journal of …, 2020 - nature.com
Background Immune response against cancer has prognostic impact but its role in gastric
cancer is poorly known. The aim of the study was to assess the prognostic significance of …
cancer is poorly known. The aim of the study was to assess the prognostic significance of …
[HTML][HTML] Immune cell infiltrate and prognosis in gastric cancer
N Kemi, N Hiltunen, J P. Väyrynen, VM Pohjanen… - Cancers, 2020 - mdpi.com
Simple Summary Differences in the composition of immune cell infiltrate between individual
tumors have been shown to have prognostic significance in several cancer types. In gastric …
tumors have been shown to have prognostic significance in several cancer types. In gastric …
Exercise capacity in the stair-climbing test predicts outcomes of operable esophageal cancer in minimally invasive era
A Junttila, O Helminen, J Mrena, E Sihvo - European Journal of Surgical …, 2022 - Elsevier
Introduction The risk of complications after esophagectomy highlights the need for careful
preoperative assessment. Aim was to assess whether stair-climbing test (SCT) could predict …
preoperative assessment. Aim was to assess whether stair-climbing test (SCT) could predict …
Implementation of multimodality therapy and minimally invasive surgery: short-and long-term outcomes of gastric cancer surgery in Medium-Volume center
A Junttila, O Helminen, V Kairaluoma, A Mattila… - Journal of …, 2022 - Elsevier
Background Multimodal treatment of gastric cancer includes careful preoperative staging,
perioperative oncological treatment, and selective minimally invasive approach. The aim …
perioperative oncological treatment, and selective minimally invasive approach. The aim …
[HTML][HTML] Postoperative Complications After Neoadjuvant Chemotherapy Versus Upfront Surgery in Gastric Adenocarcinoma: A Population-Based Nationwide Study in …
E Putila, O Helminen, M Helmiö, H Huhta… - Annals of Surgical …, 2024 - Springer
Background To date, no large population-based studies have compared complications and
short-term outcomes between neoadjuvant chemotherapy and upfront surgery in gastric …
short-term outcomes between neoadjuvant chemotherapy and upfront surgery in gastric …
[HTML][HTML] Long-term survival after transhiatal versus transthoracic esophagectomy: a population-based nationwide study in Finland
A Junttila, O Helminen, M Helmiö, H Huhta… - Annals of Surgical …, 2022 - Springer
Background No population-based studies comparing long-term survival after transhiatal
esophagectomy (THE) and transthoracic esophagectomy (TTE) exist. This study aimed to …
esophagectomy (THE) and transthoracic esophagectomy (TTE) exist. This study aimed to …
Five-year survival after McKeown compared to Ivor-Lewis esophagectomy for esophageal cancer: a population-based nationwide study in Finland
A Junttila, O Helminen, M Helmiö, H Huhta… - Annals of …, 2023 - journals.lww.com
Objective: The aim of study was to compare overall 5-year survival of esophageal cancer
patients undergoing transthoracic esophagectomy with either neck or intrathoracic …
patients undergoing transthoracic esophagectomy with either neck or intrathoracic …
[HTML][HTML] Stapled vs handsewn anastomosis and anastomotic leaks in gastric cancer surgery—a population-based nationwide study in Finland
E Kvist, O Helminen, M Helmiö, H Huhta… - Journal of …, 2024 - Elsevier
Background There is a lack of evidence regarding anastomotic technique and postoperative
complications in gastric cancer surgery. This study aimed to evaluate whether there are …
complications in gastric cancer surgery. This study aimed to evaluate whether there are …