Long-Haul Post-COVID-19 Symptoms Presenting as a Variant of Postural Orthostatic Tachycardia Syndrome: The Swedish Experience

Madeleine Johansson; Marcus Ståhlberg; Michael Runold; Malin Nygren-Bonnier; Jan Nilsson; Brian Olshansky; Judith Bruchfeld; Artur Fedorowski

doi:10.1016/j.jaccas.2021.01.009

Long-Haul Post-COVID-19 Symptoms Presenting as a Variant of Postural Orthostatic Tachycardia Syndrome: The Swedish Experience

JACC Case Rep. 2021 Apr;3(4):573-580. doi: 10.1016/j.jaccas.2021.01.009. Epub 2021 Mar 10.

Authors

Madeleine Johansson^{1

2}, Marcus Ståhlberg^{3

4}, Michael Runold⁵, Malin Nygren-Bonnier^{6

7}, Jan Nilsson¹, Brian Olshansky⁸, Judith Bruchfeld^{9

10}, Artur Fedorowski^{1

2}

Affiliations

¹ Department of Clinical Sciences, Faculty of Medicine, Lund University, Malmö, Sweden.
² Department of Cardiology, Skåne University Hospital, Malmö, Sweden.
³ Heart, Vascular, and Neuro Theme, Karolinska University Hospital, Stockholm, Sweden.
⁴ Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
⁵ Department of Respiratory and Allergic Diseases, Karolinska University Hospital, Stockholm, Sweden.
⁶ Department of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
⁷ Function Allied Health Professionals, Medical Unit Occupational Therapy and Physiotherapy, Karolinska University Hospital, Stockholm, Sweden.
⁸ Department of Internal Medicine, Division of Cardiology, University of Iowa Hospitals, Iowa City, Iowa.
⁹ Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden.
¹⁰ Division of Infectious Diseases, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.

Abstract

Major clinical centers in Sweden have witnessed an inflow of patients with chronic symptoms following initial outpatient care for coronavirus disease-2019 (COVID-19) infection, suggestive of postural orthostatic tachycardia syndrome. This report presents the first case series of 3 Swedish patients diagnosed with postural orthostatic tachycardia syndrome more than 3 months after the primary COVID-2019 infections. (Level of Difficulty: Intermediate.).

Keywords: BP, blood pressure; COVID-19 infection; COVID-19, coronavirus disease-2019; HR, heart rate; POTS, postural orthostatic tachycardia syndrome; SARS-CoV-2, severe acute respiratory syndrome-coronavirus-2; autonomic dysfunction; complications; orthostatic intolerance; postural orthostatic tachycardia syndrome.

Publication types

Case Reports