Endogenous endophthalmitis: diagnosis, management, and prognosis

Mohammad Ali Sadiq; Muhammad Hassan; Aniruddha Agarwal; Salman Sarwar; Shafak Toufeeq; Mohamed K Soliman; Mostafa Hanout; Yasir Jamal Sepah; Diana V Do; Quan Dong Nguyen

doi:10.1186/s12348-015-0063-y

Endogenous endophthalmitis: diagnosis, management, and prognosis

J Ophthalmic Inflamm Infect. 2015 Dec;5(1):32. doi: 10.1186/s12348-015-0063-y. Epub 2015 Nov 3.

Authors

Affiliations

¹ Ocular Imaging Research and Reading Center, Stanley M. Truhlsen Eye Institute, University of Nebraska Medical Center, 3902 Leavenworth Street, Omaha, NE, 68105, USA. ali.sdq@hotmail.com.
² Ocular Imaging Research and Reading Center, Stanley M. Truhlsen Eye Institute, University of Nebraska Medical Center, 3902 Leavenworth Street, Omaha, NE, 68105, USA. muhammadhassan070@gmail.com.
³ Ocular Imaging Research and Reading Center, Stanley M. Truhlsen Eye Institute, University of Nebraska Medical Center, 3902 Leavenworth Street, Omaha, NE, 68105, USA. aniruddha9@gmail.com.
⁴ Ocular Imaging Research and Reading Center, Stanley M. Truhlsen Eye Institute, University of Nebraska Medical Center, 3902 Leavenworth Street, Omaha, NE, 68105, USA. salman.sarwar@gmail.com.
⁵ Ocular Imaging Research and Reading Center, Stanley M. Truhlsen Eye Institute, University of Nebraska Medical Center, 3902 Leavenworth Street, Omaha, NE, 68105, USA. shafak.toufeeq@nhs.net.
⁶ Ocular Imaging Research and Reading Center, Stanley M. Truhlsen Eye Institute, University of Nebraska Medical Center, 3902 Leavenworth Street, Omaha, NE, 68105, USA. mhmd_soliman@hotmail.com.
⁷ Department of Ophthalmology, Assiut University Hospital, Assiut University, Assiut, Egypt. mhmd_soliman@hotmail.com.
⁸ Ocular Imaging Research and Reading Center, Stanley M. Truhlsen Eye Institute, University of Nebraska Medical Center, 3902 Leavenworth Street, Omaha, NE, 68105, USA. mostafa.hanout@gmail.com.
⁹ Ocular Imaging Research and Reading Center, Stanley M. Truhlsen Eye Institute, University of Nebraska Medical Center, 3902 Leavenworth Street, Omaha, NE, 68105, USA. yasir.sepah@unmc.edu.
¹⁰ Ocular Imaging Research and Reading Center, Stanley M. Truhlsen Eye Institute, University of Nebraska Medical Center, 3902 Leavenworth Street, Omaha, NE, 68105, USA. diana.do@unmc.edu.
¹¹ Ocular Imaging Research and Reading Center, Stanley M. Truhlsen Eye Institute, University of Nebraska Medical Center, 3902 Leavenworth Street, Omaha, NE, 68105, USA. quan.nguyen@unmc.edu.

Abstract

Endogenous endophthalmitis is an ophthalmic emergency that can have severe sight-threatening complications. It is often a diagnostic challenge because it can manifest at any age and is associated with a number of underlying predisposing factors. Microorganisms associated with this condition vary along a broad spectrum. Depending upon the severity of the disease, both medical and surgical interventions may be employed. Due to rarity of the disease, there are no guidelines in literature for optimal management of these patients. In this review, treatment guidelines based on clinical data and microorganism profile have been proposed.

Keywords: Bacterial; Endogenous; Endophthalmitis; Fungal; Metastatic; Review.