Abstract
The importance of the Basidiomycete Cryptococcus neoformans to human health has stimulated its development as an experimental model for both basic physiology and pathogenesis. We briefly review the history of this fascinating and versatile fungus, some notable aspects of its biology that contribute to virulence, and current tools available for its study.
Keywords:
Cryptococcus gattii; Cryptococcus neoformans; capsule; cryptococcosis; meningitis; pathogenic fungus; yeast.
Copyright © 2013 John Wiley & Sons, Ltd.
Publication types
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Historical Article
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Research Support, N.I.H., Extramural
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Review
MeSH terms
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Animals
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Bacterial Proteins / genetics
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Bacterial Proteins / metabolism
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Cryptococcosis / epidemiology
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Cryptococcosis / history*
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Cryptococcosis / microbiology*
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Cryptococcus neoformans / genetics
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Cryptococcus neoformans / isolation & purification
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Cryptococcus neoformans / pathogenicity
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Cryptococcus neoformans / physiology*
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History, 19th Century
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History, 20th Century
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History, 21st Century
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Humans
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Microbiology / history*