Abstract
The differential diagnosis of SC includes malignant, premalignant, metastatic, inflammatory, and eczematoid disorders, along with photodermatoses and a few rare but important disorders of the lower lip. Current treatment options include topical, ablative, and surgical therapies. Several clinical challenges are also addressed, including the issue of obtaining a high-yield diagnostic biopsy specimen while minimizing patient morbidity, field-directed treatment for SC, and strategies for combination therapy.
Copyright © 2011 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.
MeSH terms
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Administration, Topical
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Aminoquinolines / administration & dosage
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Aminoquinolines / therapeutic use
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Biopsy
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Carcinoma, Squamous Cell / therapy*
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Cheilitis / pathology
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Cheilitis / surgery
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Cheilitis / therapy*
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Combined Modality Therapy
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Diagnosis, Differential
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Diclofenac / administration & dosage
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Diclofenac / therapeutic use
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Female
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Fluorouracil / administration & dosage
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Fluorouracil / therapeutic use
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Humans
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Imiquimod
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Lip Neoplasms / therapy*
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Male
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Middle Aged
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Precancerous Conditions / therapy
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Skin Neoplasms / therapy*
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Sunlight / adverse effects
Substances
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Aminoquinolines
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Diclofenac
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Imiquimod
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Fluorouracil