Pediatric endophthalmitis. A 10-year consecutive series

Retina. 2008 Mar;28(3 Suppl):S3-7. doi: 10.1097/IAE.0b013e318159ec7f.

Abstract

Purpose: To report the etiology, culture results, management techniques, and visual outcomes for pediatric endophthalmitis at Emory University for the past 10 years.

Methods: Retrospective chart review based on a computer generated database of all cases of endophthalmitis occurring in patients younger than 18 years from 1995 to 2005.

Results: Sixteen cases of pediatric endophthalmitis were identified. Ocular trauma and previous ocular surgery were the most common etiologies, accounting for 44% and 38% of cases respectively. Nine cases (56%) had positive vitreous cultures. Sixty-six percent of cases with positive vitreous cultures involved Gram-positive species. All patients were treated with intravitreal antibiotics. Primary vitrectomy was performed in nine cases. Subsequent to the intraocular infection, 6 eyes (38%) developed retinal detachments. At last follow-up, visual acuity of 20/400 or better was obtained in only 6 eyes (38%).

Conclusions: Pediatric endophthalmitis in this series most commonly resulted from penetrating ocular trauma or from ocular surgery. Retinal detachment commonly occurred as a complication. Despite aggressive management with antibiotics and in many cases vitrectomy, visual outcomes were poor in this series.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Endophthalmitis* / complications
  • Endophthalmitis* / drug therapy
  • Endophthalmitis* / etiology
  • Endophthalmitis* / surgery
  • Eye Injuries / complications
  • Female
  • Humans
  • Infant
  • Male
  • Ophthalmologic Surgical Procedures / adverse effects
  • Retinal Detachment / etiology
  • Retrospective Studies
  • Treatment Outcome
  • Vitrectomy*