Small colony variants of Staphylococcus aureus and pacemaker-related infection

Emerg Infect Dis. 2003 Oct;9(10):1316-8. doi: 10.3201/eid0910.0302000.

Abstract

We describe the first known case of a device-related bloodstream infection caused by Staphylococcus aureus small colony variants. Recurrent pacemaker-related bloodstream infection within a 7-month period illustrates the poor clinical and microbiologic response to prolonged antimicrobial therapy in a patient infected with this S. aureus subpopulation.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Bacteremia / drug therapy
  • Bacteremia / etiology*
  • Bacteremia / microbiology
  • Genetic Variation
  • Humans
  • Male
  • Middle Aged
  • Pacemaker, Artificial / adverse effects*
  • Recurrence
  • Staphylococcal Infections / drug therapy
  • Staphylococcal Infections / etiology*
  • Staphylococcal Infections / microbiology
  • Staphylococcus aureus / genetics
  • Staphylococcus aureus / growth & development
  • Staphylococcus aureus / isolation & purification*

Substances

  • Anti-Bacterial Agents