Abstract
Neonatal Citrobacter koseri (diversus) meningitis is often complicated by the formation of brain abscesses and has a poor neurological outcome with seizures, mental retardation and paresis as sequelae in 50% of the cases. As there is emerging resistance to ampicillin, gentamicin and third-generation cephalosporins, we attempted to treat this infection with carbapenems. Carbapenems in combination with cefotaxime and surgical drainage may play an important role in treating C. koseri meningitis.
MeSH terms
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Carbapenems / therapeutic use*
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Cefotaxime / therapeutic use*
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Cephalosporins / therapeutic use*
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Citrobacter / isolation & purification
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Citrobacter / pathogenicity*
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Combined Modality Therapy
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Drainage
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Enterobacteriaceae Infections / drug therapy*
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Enterobacteriaceae Infections / pathology
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Enterobacteriaceae Infections / surgery
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Female
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Humans
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Infant, Newborn
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Meningitis, Bacterial / drug therapy*
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Meningitis, Bacterial / pathology
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Meningitis, Bacterial / surgery
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Prognosis
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Treatment Outcome
Substances
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Carbapenems
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Cephalosporins
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Cefotaxime