Disorders of frontal lobe functioning

Semin Neurol. 2000;20(4):427-37. doi: 10.1055/s-2000-13175.

Abstract

The neurology of frontal lobe disorders can be summarized in descriptions of behavioral problems (apathy, etc.), of cognitive impairments (poor planning, etc.), and of motor deficits (grasp reflex, etc.). Reviews of this sort do not indicate, however, any regional specificity to the deficit profiles or identify any of the component processes of the complex deficits-what exactly is "poor planning"? In this review we present specific steps that assist in overcoming the limitations: (1) identify weaknesses in current understanding, (2) operationally define the processes to be analyzed, (3) review some methodologies that allow parsing of discreet processes into specific frontal regions, (4) review the unique advantages and disadvantages of the various neurological disorders that provide us with subjects for study, and (5) propose approaches to advance further a useful clinical neurology of frontal lobe disorders as well as a more finely grained scientific description of core frontal processes.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aphasia / etiology
  • Aphasia / pathology
  • Aphasia / physiopathology
  • Attention Deficit Disorder with Hyperactivity / etiology
  • Attention Deficit Disorder with Hyperactivity / pathology
  • Attention Deficit Disorder with Hyperactivity / physiopathology
  • Behavioral Symptoms / etiology*
  • Behavioral Symptoms / pathology
  • Behavioral Symptoms / physiopathology*
  • Brain Injuries / complications
  • Brain Injuries / pathology
  • Brain Injuries / physiopathology
  • Cognition Disorders / etiology*
  • Cognition Disorders / pathology
  • Cognition Disorders / physiopathology*
  • Consciousness Disorders / etiology
  • Consciousness Disorders / pathology
  • Consciousness Disorders / physiopathology
  • Dementia / complications
  • Dementia / pathology
  • Dementia / physiopathology
  • Frontal Lobe / pathology*
  • Frontal Lobe / physiopathology*
  • Humans
  • Memory Disorders / etiology
  • Memory Disorders / pathology
  • Memory Disorders / physiopathology
  • Movement Disorders / etiology*
  • Movement Disorders / pathology
  • Movement Disorders / physiopathology*
  • Neoplasms / complications
  • Neoplasms / pathology
  • Neoplasms / physiopathology
  • Stroke / complications
  • Stroke / pathology
  • Stroke / physiopathology