Unusual radiological presentation and rapid fatal progression of invasive pulmonary aspergillosis in an immunocompetent young patient

Respirology. 1999 Sep;4(3):287-90. doi: 10.1046/j.1440-1843.1999.00192.x.

Abstract

Invasive aspergillosis occurs very rarely in immunocompetent hosts. We describe a 21-year-old female with no obvious immunosuppression or underlying lung disease, who presented with minimal symptoms and bilateral hilar prominence on chest X-ray. Invasive aspergillosis was diagnosed on an open lung biopsy. She deteriorated in the ensuing 2 weeks and died of a sudden massive haemoptysis. This initial radiological abnormality and the rapid clinical course of the disease in young immunocompetent patients have not been previously reported.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aspergillosis / diagnostic imaging*
  • Aspergillosis / pathology
  • Aspergillus fumigatus*
  • Disease Progression
  • Fatal Outcome
  • Female
  • Hemoptysis / etiology
  • Humans
  • Immunocompetence*
  • Lung / pathology
  • Lung Diseases, Fungal / diagnostic imaging*
  • Lung Diseases, Fungal / pathology
  • Tomography, X-Ray Computed