Mucosa-Associated Lymphoid Tissue Type Lymphoma of the Gallbladder Associated with Acute Myeloid Leukemia

Yasunobu ABE; Hiroshi TAKATSUKI; Yasuyo OKADA; Atsushi SAITO; Toshinari KIMURA; Junji NISHIMURA

doi:10.2169/internalmedicine.38.442

Yasunobu ABE, Hiroshi TAKATSUKI, Yasuyo OKADA, Atsushi SAITO, Toshinari KIMURA, Junji NISHIMURA

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Keywords: gallbladder tumor, lymphoma with myeloid leukemia

JOURNAL FREE ACCESS

1999 Volume 38 Issue 5 Pages 442-444

DOI https://doi.org/10.2169/internalmedicine.38.442

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Abstract

We describe a patient with mucosa-associated lymphoid tissue (MALT) type lymphoma of the gallbladder who developed concurrent acute myeloid leukemia (M2). She was admitted because of progressive jaundice and underwent cholecystectomy. Histologic examination of the gallbladder showed diffuse proliferation of atypical lymphoid cells and a formed lymphoepithelial lesion. Because of progressive thrombocytopenia, a bone marrow tap was performed 25 days after the operation. Bone marrow contained 65.5% blasts, and was positive for peroxidase, CD33 and HLA-DR, and negative for lymphoid markers. We discuss the rare association of these disorders.
(Internal Medicine 38: 442-444, 1999)

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