Chest
Selected ReportsMediastinal Lipomatosis in Simple Obesity
Section snippets
CASE REPORT
A 36-year-old white man entered the hospital because of chest discomfort of three months’ duration. There had been some recent occasional chest pain radiating towards the left arm. There were no complaints of dysphagia or dyspnea. The patient, who had never received any systemic steroid therapy, began to gain weight during the preceding three years. His past history was noncontributory. Physical examination revealed a well-developed, well-nourished obese man in no acute distress. Physical
DISCUSSION
Koerner and Sun2 reported three cases of mediastinal lipomatosis following large doses of systemic corticosteroid therapy. Thereafter, several authors1, 3, 4, 5, 6 reported a number of similar cases. All reported cases had in common some evidence of clinical Cushing's syndrome (either primary or iatrogenic).
In simple obesity, excessive fat is generally stored at various body sites, notably in the subcutaneous tissue, omentum, mesentery, and perirenal tissue. Although more fatty tissue may be
References (6)
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Widening of the mediastinum resulting from fat accumulation
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Mediastinal lipomatosis secondary to steroid therapy
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Mediastinal widening in iatrogenic Cushing's syndrome
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Cited by (25)
Mediastinal Lipomatosis Presenting as Persistent Pneumonia
2015, Journal of PediatricsCorticosteroid-induced mediastinal lipomatosis in a patient with overlap syndrome (autoimmune hepatitis-primary biliary cirrhosis)
2011, Gastroenterologia y HepatologiaAtypical mediastinal lipomatosis
2007, Heart and Lung: Journal of Acute and Critical CareCitation Excerpt :ML is suggested by widening of the mediastinum bilaterally with smooth and sharply defined contours and absence of a definable mass on lateral view.6 The fat shadow is often poorly defined, creating a “double contour” effect,1 and is not as dense as other superior mediastinal masses3,4,6; however, lucency may not be as obvious because of the underlying lucent pulmonary tissue.3 This may also be called the “double contour” effect.
Lipodystrophic syndrome associated with infection with the human immunodeficiency virus and mediastinal lipomatosis [4]
2003, Revista Clinica EspanolaSebaceous naevus of Jadassohn and primary mediastinal lipomatosis
1993, British Journal of Plastic Surgery