Special Issue: KDIGO Clinical Practice Guideline for the Care of Kidney Transplant Recipients

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Abstract

The 2009 Kidney Disease: Improving Global Outcomes (KDIGO) clinical practice guideline on the monitoring, management, and treatment of kidney transplant recipients is intended to assist the practitioner caring for adults and children after kidney transplantation. The guideline development process followed an evidence-based approach, and management recommendations are based on systematic reviews of relevant treatment trials. Critical appraisal of the quality of the evidence and the strength of recommendations followed the Grades of Recommendation Assessment, Development, and Evaluation (GRADE) approach. The guideline makes recommendations for immunosuppression, graft monitoring, as well as prevention and treatment of infection, cardiovascular disease, malignancy, and other complications that are common in kidney transplant recipients, including hematological and bone disorders. Limitations of the evidence, especially on the lack of definitive clinical outcome trials, are discussed and suggestions are provided for future research.

Keywords

Guideline
KDIGO
kidney transplant recipient care
immunosuppression
graft monitoring
infectious diseases
cardiovascular disease
malignancy
mineral and bone disorder
hematological complications
hyperuricemia
gout
growth
sexual function
fertility
mental health

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