Transactions of the Sixty-fourth Annual Meeting of the South Atlantic Association of Obstetricians and GynecologistsPaget's disease of the vulva☆
Section snippets
Material and methods
Our vulvar cancer database was reviewed, and women with extramammary Paget's disease of the vulva who were treated at the Division of Gynecologic Oncology during the period 1988 to 2000 were identified. The charts of these patients were reviewed, and data were collected regarding patient demographics, previous Paget's treatment, patient symptoms, surgical margin status, associated malignancies, and time to recurrence.
Surgical treatment included wide local excision for these lesions with a small
Results
Twenty-three women with extramammary Paget's disease of the vulva and perineum were treated during the 12-year period. Four of these patients had been treated previously for Paget's disease before our involvement. All the women were white. The average age of onset of symptoms was 68 years (median, 69 years; range, 46-84 years). The most common symptoms were a lesion (87%) and itching (78%). Other symptoms included a burning sensation (52%), dysuria (4%), and a watery discharge (4%). Symptoms
Comment
Paget's disease of the vulva remains a rare condition. The literature consists of only small case series. The demographics and disease characteristics of our patients are consistent with published reports.2, 3, 4 This is classically a postmenopausal disease, but it has been reported in a 35-year-old woman.5 Most of our patients experienced itching and burning and had a lesion.
There was a significant delay between the onset of symptoms and diagnosis. This delay did not correlate with the size or
References (12)
- et al.
Paget's disease of the vulva: prevalence of associated vulvar adenocarcinoma, invasive Paget's disease, and recurrence after surgical excision
Am J Obstet Gynecol
(1999) - et al.
Conservative management of extramammary Paget's disease of the vulva
Gynecol Oncol
(1989) - et al.
Paget's disease of the vulva
Gynecol Oncol
(1975) - et al.
Paget's disease of the vulva
Gynecol Oncol
(1990) - et al.
Vulvar Paget's disease: the need to exclude an invasive lesion
Gynecol Oncol
(1990) - et al.
Malignancies of the vulva
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