Elsevier

Fertility and Sterility

Volume 95, Issue 2, February 2011, Pages 762-766
Fertility and Sterility

Reproductive surgery
Evaluation of loop ligation of larger myoma pseudocapsule combined with vasopressin on laparoscopic myomectomy

https://doi.org/10.1016/j.fertnstert.2010.08.059Get rights and content
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Objective

To study the effects of reducing hemorrhage by loop ligation of larger myoma pseudocapsules combined with vasopressin on laparoscopic myomectomy (LM).

Design

Prospective controlled clinical trial.

Setting

Sheng Jing Hospital, China Medical University.

Patient(s)

A total of 105 women with symptomatic single or multiple larger myomas (diameter 6–18 cm) in need of surgical intervention, who wished to retain their uteri, were randomly divided into three groups in our hospital from January 2006 to January 2008: A) loop ligation combined with vasopressin; B) vasopressin alone; and C) neither loop ligation nor vasopressin. All patients were treated by LM. Each group included 35 cases.

Intervention(s)

Loop ligation of larger myoma (6–18 cm) pseudocapsule combined with vasopressin before thoroughly enucleating the myoma.

Main Outcome Measure(s)

Operating time, blood loss, blood transfusion, postoperative stay in hospital, symptom improvement.

Result(s)

Average blood loss, postoperative stay in hospital, number of conversions to laparotomy, and need for transfusion because of bleeding during operation in group A were significantly lower than in groups B and C. All patients in group A underwent technically successful laparoscopic operations.

Conclusion(s)

Loop ligation of larger myoma pseudocapsules combined with vasopressin is a safe, effective, and promising new method to reduce bleeding during laparoscopic myomectomy and makes the laparoscopic operations with larger myomas easier.

Key Words

Loop ligation
myoma
myomectomy
laparoscope

Cited by (0)

F.Z. has nothing to disclose. Y.J. has nothing to disclose. Z.G. has nothing to disclose. R.H. has nothing to disclose. M.W. has nothing to disclose.