Original articleImplantable Telescope for End-Stage Age-related Macular Degeneration: Long-term Visual Acuity and Safety Outcomes
Section snippets
Methods
The study device, design, patient screening, surgical procedure, postoperative management, examination methods, and statistical methods have been described previously.12 The study device creates a new classification of ophthalmic surgical prosthetics—a telescope prosthesis. Fellow eyes served as a comparison because both eyes were required to have stable, untreatable AMD and central vision loss. Patients returned for examinations at 18 and 24 months after implantation to assess long-term visual
Demographics and Patient Retention
Baseline characteristics, demographic information, and operative results for this end-stage AMD study population (central scotomas resulting from bilateral geographic atrophy or disciform scars and bilateral BCVA from 20/80 to 20/800) have been described previously in detail.12 Overall, data from 174 (92.6%) of 188 available patients at two years were analyzed, or 84.5% of the original 206 implanted patients. Specifically, of the 206 patients implanted with the telescope prosthesis, 10 (4.9%)
Discussion
The current report on this prosthetic telescope procedure answers important questions regarding long-term safety and efficacy. Overall, similar to the one-year outcomes,12 the two-year results reflect the continued benefit of the device for this patient population with debilitating central vision loss resulting from bilateral geographic atrophy or disciform scars. Two-year endothelial cell counts and pachymetry further support the hypothesis that ECD is reduced during surgery, but then
Henry L. Hudson, MD, FACS, is in private practice in Tucson, Arizona. He completed his medical degree at USC, followed by post-graduate studies at UCLA, Doheny Eye Institute, USC and Retina Vitreous Associates in Los Angeles. Currently, Dr Hudson belongs to many ophthalmologic societies and has published several articles in peer-reviewed journals. He is also the lead Principal Investigator of numerous clinical research studies for the treatment of vitreo-retinal diseases and conditions.
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Henry L. Hudson, MD, FACS, is in private practice in Tucson, Arizona. He completed his medical degree at USC, followed by post-graduate studies at UCLA, Doheny Eye Institute, USC and Retina Vitreous Associates in Los Angeles. Currently, Dr Hudson belongs to many ophthalmologic societies and has published several articles in peer-reviewed journals. He is also the lead Principal Investigator of numerous clinical research studies for the treatment of vitreo-retinal diseases and conditions.