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Depression, physical activity, energy consumption, and quality of life in OSA patients before and after CPAP treatment

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Abstract

Background

A variety of studies have demonstrated improvement in quality of life and depressive symptoms in obstructive sleep apnea (OSA) patients after continuous positive airway pressure (CPAP) treatment. However, very little is known about the effect of OSA treatment on physical activity and energy consumption.

Objectives

The aim of this study was to evaluate the changes in depression, physical activity, energy expenditure, and quality of life (QoL) in OSA patients before and after CPAP therapy.

Methods

Forty-one patients with OSA as revealed by polysomnography, were included to the study. They responded to the generic World Health Organization Quality of Life (WHOQoL) questionnaire, to the specific-disease Quebec Sleep Questionnaire, and to Center for Epidemiologic Studies Depression Scale (CES-D) in order to evaluate QoL and the incidence of depression. In addition, all patients wore an accelerometer which measured physical activity and energy expenditure during a week. At least 6 months after initiation of CPAP treatment (mean time, 9 months) we re-examined 24 patients who met the compliance with the treatment criteria.

Results

Patients after CPAP therapy had significantly higher scores in all domains of the Quebec Sleep Questionnaire and in the domains of physical health/level of independence and psychological health/spirituality of the WHOQoL. Depression scores were also better in CES-D after treatment. However, despite the improvement in QoL and psychological status, CPAP therapy had no impact on physical activity and energy expenditure.

Conclusions

CPAP therapy improves QoL and lessens depressive symptoms in our group of well-treated OSA patients. However, physical activity and energy expenditure did not present statistically significant improvement in the same group of OSA patients.

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Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. 1st Department of Respiratory Medicine, Medical School, “Sotiria” Hospital for Chest Diseases, National and Kapodistrian University of Athens, 152, Mesogion Av, 115 27, Athens, Greece

    C. Diamanti, E. Manali, K. Cholidou, E. Markozannes, P. Bakakos & M. Alchanatis

  2. 1st Department of Psychiatry, Medical School, Eginition Hospital, National and Kapodistrian University of Athens, 72-74 Vas. Sofias Av, 11528, Athens, Greece

    M. Ginieri-Coccossis & I. Liappas

  3. Genomics and Proteomics Research Units, Center of Basic Research II, Biomedical Research Foundation, Academy of Athens, Soranou Efessiou 4, 115 27, Athens, Greece

    K. Vougas

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  1. C. Diamanti
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  2. E. Manali
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  3. M. Ginieri-Coccossis
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  4. K. Vougas
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  5. K. Cholidou
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  6. E. Markozannes
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  8. I. Liappas
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  9. M. Alchanatis
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Correspondence to C. Diamanti.

Additional information

The institution at which the work was performed is 1st Department of Respiratory Medicine, Medical School, National and Kapodistrian University of Athens, “Sotiria” Hospital for Chest Diseases.

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Diamanti, C., Manali, E., Ginieri-Coccossis, M. et al. Depression, physical activity, energy consumption, and quality of life in OSA patients before and after CPAP treatment. Sleep Breath 17, 1159–1168 (2013). https://doi.org/10.1007/s11325-013-0815-6

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  • DOI: https://doi.org/10.1007/s11325-013-0815-6

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