Summary of the biochemical and haematological investigation findings
| Parameter | Infant A (4 months) | Infant B (7 months) | Reference limits |
| Indicators of muscle damage | |||
| Creatine kinase (U/L) | 942 | 616 | 20–180 |
| Lactate dehydrogenase (U/L) | 780 | 540 | 180–430 |
| Aspartate transaminase (U/L) | 331 | 240 | <35 |
| Liver parameters | |||
| Alanine transaminase (U/L) | 112 | 107 | <35 |
| Alkaline phosphatase (U/L) | 181 | 437 | 60–425 |
| Gamma-glutamyltransferase (U/L) | 13 | 125 | 5–32 |
| Total bilirubin (μmol/L) | 9 | 9 | 3–20 |
| Total protein (g/L) | 51 | 50 | 60–80 |
| Albumin (g/L) | 36 | 37 | 34–50 |
| Renal parameters and electrolytes | |||
| Creatinine (μmol/L) | 50 | 31 | 35–40 |
| Urea (mmol/L) | 1.5 | 1.7 | 1.5–3.0 |
| Sodium (mmol/L) | 140 | 134 | 135–145 |
| Potassium (mmol/L) | 3.9 | 4.5 | 3.5–5.3 |
| Total calcium (mmol/L) | 2.46 | – | 2.2–2.7 |
| Phosphate (mmol/L) | 1.28 | – | 1.45–2.16 |
| Haematological parameters | |||
| Haemoglobin (g/L) | 121 | 107 | 140–240 |
| White cell count (×109/L) | 5.8 | 8.4 | 3.1–21.6 |
| Platelets (×109/L) | 571 | 342 | 152–472 |
| Metabolic parameters | |||
| Total cholesterol (mmol/L) | 5.76 | 5.25 | 1.71–5.91 |
| Triglyceride (mmol/L) | 1.6 | 1.5 | 0.62–3.12 |
| Random glucose (mmol/L) | 5.4 | 6.3 | 3.3–11.1 |
| Ketone bodies* | Negative | Negative | Negative |
| Uric acid (μmol/L) | 303 | 233 | 119–327 |
| Ammonia (μmol/L) | 67 | 74 | 40–80 |
| Acid-base parameters (with respiratory support) | |||
| pH | 7.382 | 7.405 | 7.35–7.45 |
| PaO2 (mm Hg) | 103 | 95 | 75–100 |
| PaCO2 (mm Hg) | 30.2 | 36.1 | 35–45 |
| Bicarbonate (mmol/L) | 18.1 | 22.8 | 22–26 |
| Base excess (mmol/L) | −5.4 | −3.2 | (−2) – (+2) |
| Lactate (mmol/L) | 1.50 | 1.30 | 0.5–2.22 |
| Acid-base parameters (at the acute presentation with respiratory distress) | |||
| pH | 7.325 | 7.039 | 7.35–7.45 |
| PaO2 (mm Hg) | 80.5 | 22.6 | 75–100 |
| PaCO2 (mm Hg) | 55.9 | 80.7 | 35–45 |
| Bicarbonate (mmol/L) | 17.4 | 22.0 | 22–26 |
| Base excess (mmol/L) | −2.8 | −8.9 | (−2) – (+2) |
| Lactate (mmol/L) | 1.80 | 7.30 | 0.5–2.22 |
| Indicators of infection | |||
| ESR (mm/first hour) | 2 | - | <10 |
| C reactive protein (mg/L) | 1.5 | 17.4 | <5 |
All investigations were conducted on blood specimens (serum/plasma/whole blood).
*Investigations conducted on urine specimens
ESR, erythrocyte sedimentation rate; PaCO2, Arterial partial pressure of carbon dioxide; PaO2, Arterial partial pressure of oxygen.