Variable | Our patient results | Score | Comment |
Morphology | |||
Pustules | Typical | +2 | Typical non-follicular sterile |
Erythema | Typical | +2 | Diffuse |
Distribution/pattern | Typical | +2 | Trunk, limbs, skin folds |
Post-pustular desquamation | Yes | +1 | Extensive |
Course | |||
Mucosal involvement | No | 0 | |
Acute onset (<10 days) | Yes | 0 | |
Resolution of pustules and erythema <15 days | Yes | 0 | |
Fever >38°C | Yes | +1 | |
Polymorphonuclear neutrophils >7000/mm3 | Yes | +1 | |
Histology | |||
Spongiform, subcorneal pustule(s) with papillary oedema, perivascular infiltrates of neutrophils | Yes | +3 | |
Overall score (−18 to +12) | 12 | ||
Overall score of −10 to 0 indicates no acute generalised exanthematous pustulosis Score 1–4 ‘Possible’ Score 5–7 ‘Probable’ Score 8–12 ‘Definite’ |
Giving the probability of AGEP diagnosis.
AGEP, acute generalised exanthematous pustulosis.